Azithromycin: Instructions For Use, How To Take

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Azithromycin: Instructions For Use, How To Take
Azithromycin: Instructions For Use, How To Take

Video: Azithromycin: Instructions For Use, How To Take

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Video: Azithromycin: How to Use, When to Use, and Side Effects || Covid-19 || Practo 2023, February

And zithromycin tablets are prescribed for a large list of diseases caused by bacteria, parasites, and protozoa. Acts quickly, but has contraindications, therefore, you must strictly follow the doctor's instructions regarding the dosage and duration of admission. The abstract will help to study the main features of taking a medication.


  • 1 Characteristics of the medication
  • 2 Action within the body
  • 3 Areas of drug use
  • 4 Terms of use
  • 5 Interaction with other medications
  • 6 Replacement options
  • 7 Prevention of side effects

Characteristics of the medication

Azithromycin is a broad-spectrum antibiotic. You can choose a convenient shape. Manufacturers release the medicine in tablets, capsules, in the form of a powder for diluting a suspension and a solution for injection. Belongs to the class of macrolides. Leads to the complete destruction of pathogens when they accumulate in inflammatory areas.

The capsules are covered with a gelatinous shell, inside is a gray-white powder. Azithromycin capsules 500 mg are packaged by manufacturers in 3 or 6 pieces, the shell is blue. The capsule with a dosage of 0.25 g is covered with a red shell. The drug in capsules differs only in auxiliary components, which help to have the maximum detrimental effect on pathogens.

The dosage of the powder for the preparation of the suspension is 100 mg or 200 mg in 5 ml. The drug is indicated on the Forte package. The kit includes a measuring spoon and a syringe for correct dilution of the powder.

Action within the body

The antibiotic Azithromycin inhibits the development of bacteria, stops their vital activity. The activity extends to streptococci, chlamydia, mycoplasma, ureaplasma, whooping cough, hemophilus influenzae and other microorganisms.


The description of the drug allows us to note the positive aspects that distinguish it from other antibiotics.

Easily penetrates tissues and affected cells in a short time. The drug Azithromycin has the peculiarity of accumulating in the places where pathogens are located, leading to their rapid death. As a result, the negative effects of the antibiotic on the liver, spleen and heart are reduced.

The drug used has an immunomodulatory effect, therefore it is often prescribed for recurrent forms of various infections. After taking the last dose, the high concentration of the active substance remains for about a week. It is excreted along with bile and urine.

Areas of use of the drug

Azithromycin has indications for use in infectious and inflammatory diseases of various organs:

  • diseases of the paranasal sinuses: sinusitis, sinusitis, ethmoiditis;
  • diseases of the tonsils: tonsillitis, tonsillitis;
  • disease of the pharyngeal mucosa: pharyngitis;
  • otitis media: otitis media.
  • different stage of bronchitis;
  • inflammation of the lung tissue: pneumonia.
  • dermatitis;
  • erysipelas;
  • boils.

Diseases of the urogenital tract, most often caused by chlamydia, ureaplasma or mycoplasma: urethritis, cervicitis, cystitis.

Other antibiotic prescriptions include:

  • a disease caused by streptococcus - scarlet fever;
  • inflammation caused by borreliosis;
  • diseases of the digestive tract (ulcer, gastritis), provoked by Helicobacter bacteria.

The choice of a drug during the treatment of diseases caused by parasites is justified by several points:

  • fast absorption time from the digestive tract, slowly excreted from the body, does not break down under the influence of an acidic environment;
  • in severe cases, Azithromycin is allowed to be administered inside the vein, which increases the effectiveness of treatment by 65-75%;
  • a high dosage of the active substance is observed not in the blood plasma, but in the affected cell itself. As a result, the load is removed from the liver, spleen, cardiac and vascular systems;
  • the period of residence of the substance in blood plasma is about three days, and in an infected cell about 5-6 days. No other group of antibiotics has this property;
  • Azithromycin does not inhibit the activity of cells that cleanse the blood of chemical compounds.

Contraindications are severe pathological processes in the kidneys and liver, as well as the presence of high sensitivity to the entire group of macrolides.

Very often, treatment with Azithromycin is accompanied by changes in the functioning of the intestines. Diarrhea opens, discomfort worries, rumbling in the stomach. Nausea and dizziness may join. In rare cases, it can cause a malfunction of the heart and blood vessels. Possible manifestation of an allergic reaction in the form of a rash, itching.

Terms of use

For Azithromycin 500 mg tablets to work in full force, they must be taken on an empty stomach, preferably one hour before a meal or a couple of hours after a meal. The medicine is drunk once. How to take Azithromycin depends on the diagnosis, the degree of symptoms and the presence of concomitant diseases. The weight and age of the patient plays an important role.


The standard Azithromycin 500 instructions for use, which are prescribed by specialists, may be as follows.

If infectious and inflammatory processes occur in the organs of the respiratory system, ENT organs or skin, then a daily single dose of 500 mg is prescribed. It is recommended to drink before breakfast for three days.

Only three 500 mg capsules (one capsule per day) will help relieve sore throats. After the first pill is taken, after a few hours, the discomfort begins to disappear, the condition improves even with purulent angina.

In the acute severe stage of pneumonia, the use of the drug is recommended to start with the introduction of 0.5 g into a vein for two days. Then within 7-10 days you should drink the medicine in tablets. The dosage should also be 500 mg.


In diseases caused by protozoa microorganisms (chlamydia, ureaplasmosis), a different scheme is written, which depends on the form of the disease.

Ureaplasmosis should be treated comprehensively. A few days before the start of antibiotic therapy, they begin to take immunomodulators and continue to drink until the end of the entire course. Then, for five days in a row, 1 g of the drug Azithromycin is taken. Preferably before breakfast. After that, an interval of five days is maintained and another 1 g is taken. Again they take a break of five days and drink the last dosage of 1 g.

With chlamydia in Azithromycin, the instructions for use will look slightly different. If the disease proceeds without complications and is noticed in the early stages, then 1 g of Azithromycin is taken once for three days.

A sluggish form of the disease requires a different scheme. On the first day, it is recommended to take two tablets of Azithromycin 500 mg. The next two days they drink Azithromycin 0.5 g (one tablet). On the following days, 0.25 g of active ingredient is taken. The entire course of treatment lasts a week.


For complicated forms of chlamydia, Azithromycin is calculated in three doses of 1000 mg each. After taking the dosage, take a break and take the medicine again on the seventh day. A week later, one more - the last time.

Borreliosis is a focal inflammation of an infectious nature caused by ticks. Treatment involves taking a large dose of an antibiotic. Azithromycin is used once or twice a day at a dosage of 0.5 g. Treatment can range from 7-10 days. Sometimes it is prescribed in combination with Metronidazole. To prevent the development of the disease, a gel based on Azithromycin, which is applied to the area of ​​the insect bite, will help.

Sometimes the drug is given by injection. Powder in a dosage of 500 milligrams is diluted with a solvent. For three days, a therapeutic solution is injected into a vein or muscle once a day. After that, they are transferred to a tablet form. Most often, a similar treatment regimen is prescribed for diseases of the genitourinary system or in the treatment of pneumonia.

Interaction with other medications

Sometimes azithromycin should not be administered concurrently with certain other drugs:

  • enhances the effect of anticoagulants, such as Warfarin;
  • during a joint intake with Digoxin, glycosidic intoxication may appear;
  • serious pathological processes in the heart can develop while taking Disopyramide;
  • treatment in combination with the drug Rifabutin leads to leukopenia;
  • the risk of side effects increases while taking Cyclosporin;
  • not compatible with Heparin.

Replacement options

Analogues cannot be selected independently. Be sure to consult a specialist.

The antibiotic Erythromycin is used to treat infections and inflammation caused by bacteria. Prevents the appearance of streptococcal infection. There are tablets, ointment and a solution with the active substance erythromycin.


Sumamed completely repeats all the characteristics that belong to Azithromycin. Available in tablets of 125 mg or 500 mg, capsules and in powder form for suspension. The powder has a pleasant aromatic odor, and a 50 ml suspension is prepared from it.

The drug in a dosage of 250 mg is used during the treatment of an uncomplicated form of infection. Adults are most often prescribed 3 capsules, each of which is 500 mg. It is taken once for three days.

Prevention of side effects

If the patient drinks Azithromycin and its analogues, then therapy should be carried out in parallel to prevent the appearance of side effects:

  • the active substance causes disturbances in the functioning of the intestines. Be sure to take prebiotics and probiotics (Linex, Acipol, Hilak Forte, Bifidumbacterin);
  • hepatoprotectors (Essentiale, Karsil) will help reduce the activity of liver enzymes;
  • antihistamines (Suprastin, Tsetrin) will help prevent allergic reactions;
  • if there are signs of candidiasis, you need to take antifungal drugs (Nystatin, Levorin). For prevention, you can take Diflucan;
  • with higher doses of the drug, you will need the help of drugs that improve and support the work of the heart system;
  • Interferon candles will help activate the body's own defenses.

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