Azithromycin: Analogues Of The Drug, What Can Be Replaced

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Azithromycin: Analogues Of The Drug, What Can Be Replaced
Azithromycin: Analogues Of The Drug, What Can Be Replaced

Video: Azithromycin: Analogues Of The Drug, What Can Be Replaced

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Video: Azithromycin - Mechanism, side effects, precautions & uses 2023, February
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Azithromycin (analogues of which are considered in the article) belongs to the group of macrolides. It is the most popular antibiotic with a broad spectrum of action. The pronounced antibacterial effect of the drug eliminates diseases caused by different strains of pathogenic bacteria. There are many substitutes for Azithromycin, and each of them is highly effective.

Content

  • 1 Indications for use
  • 2 Similar means
  • 3 Colds
  • 4 Advantages and disadvantages

    • 4.1 The difference between Azithromycin and Sumamed
    • 4.2 The difference between Azithromycin and Amoxicillin
  • 5 Restrictions on use
  • 6 Adverse reactions
  • 7 Reviews

Indications for use

The main active ingredient of the drug

  • magnesium stearate;
  • milk sugar monohydrate;
  • microcrystalline cellulose;
  • aerosil;
  • povidone.

This antibiotic reduces the translation process to complete elimination, due to which microorganisms stop growing and multiplying. The bactericidal action of the drug is aimed at the destruction of intracellular and extracellular pathogenic bacteria.

When swallowed, the medicinal substance is rapidly absorbed from the digestive organ, since the digestive juice does not negatively affect it. Further, the drug enters the tissues through the barriers of cell membranes. The drug leaves the body through the intestines and kidneys in the same form. The antibacterial effect of the drug lasts about 5 - 7 days after its use.

Similar means

Pharmacy chains provide a large selection of products containing the active substance of the drug Azithromycin. Their difference lies solely in the concentration of the active component, the form of release, name, pricing policy.

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The most popular of them are the following drugs:

  • Sumamox;
  • "Zitrocin";
  • Sumamed;
  • Azivok;
  • "Hemomycin";
  • "Azitrox".

When choosing, for example, the drugs Azithromycin or Azitrox, it should be noted that one drug is a budget substitute for the second. There are other analogues of the antibiotic: Sumametsin, Azicid, Zetamax retard, Zitromax. These drugs are even more effective on painful cells, quickly penetrating through their hermetic membranes. These medicines are considered the best gernics.

Other substitutes for Azithromycin are antibiotics: Defens, Zit, Sumatrolide Solutab, Klabaks, Sumazil, Ketek, Fromilid, Starket, Erythromycin, Aziklar, Clarithromycin " and many others. Each drug is accompanied by instructions for use, in which you can find out all the features of the drug.

Their application is carried out in a similar way. It is advisable to take the medicine on a lean stomach (one hour before or 2 hours after a meal). For the treatment of diseases of the upper respiratory tract and ENT organs, one tablet (500 mg) of Azithromycin or its analogue is taken per day for three days. For skin diseases, the initial intake reaches 1000 mg, and then the patient needs to switch to 500 mg.

The duration of therapy is determined by the severity of the disease, the general well-being of the patient and some physiological factors. The use of a potent drug involves the mandatory simultaneous use of a probiotic. This medication maintains the normal state of the intestinal microflora, which prevents the appearance of dysbiosis.

Colds

Penicillin antibiotics (Azithromycin, Augmentin

or Amoxiclav and their substitutes) effectively resist bacteria that cause inflammation of the respiratory tract. Respiratory infections, like pneumonia, are caused by many microbes, most of which are resistant to penicillin. In this situation, the most effective effect will be Levofloxacin, Moxifloxacin.

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The class of cephalosporins is represented by the following antibiotics: "Suprax", "Zinacef", "Zinnat". They can help:

  • with pneumonia;
  • with inflammation of the pleura - the outer membrane of the lungs;
  • with inflammation of the bronchial mucosa.

Advantages and disadvantages

Azithromycin, in comparison with its counterparts, has the following advantages:

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  • affordable price (it is more profitable to use Azithromycin - an analogue of Sumamed);
  • the half-life is quite long in comparison with other similar agents;
  • the presence of a small number of adverse reactions that are extremely rare.

The disadvantages include:

  • the level of bioavailability of the drug is lower than that of other antibiotics;
  • the form of release of the drug in the form of a solution for injection and for children does not exist.

The difference between Azithromycin and Sumamed

The most famous and often prescribed substitute for Azithromycin is Sumamed. In fact, the drug Azithromycin is the first analogue of Sumamed. Therefore, they differ only in value and name. Moreover, Sumamed was subjected to clinical and laboratory research. Azithromycin has not been tested because it does not require the release of substitutes. In fact, the action of both drugs is the same.

Instructions for use states that Sumamed is prescribed for the treatment of all pathologies of the respiratory tract, urinary tract infections, skin diseases, etc. Prescribe a medication to eliminate peptic ulcer of the duodenum and stomach. Prescribe medicine for women with sexually transmitted diseases.

It has the fact that the antibiotic is taken once a day. The therapeutic course does not last long (maximum 5 days).

The difference between Azithromycin and Amoxicillin

The effect of Amoxicillin is aimed at curing inflammation of the pharyngeal mucosa, frontal sinus, pharyngeal mucosa. Azithromycin is used to treat inflammation of the paranasal sinuses of the nose, ear, pharyngitis. The effectiveness of the two drugs is quite high. To make a choice between Azithromycin and Amoxicillin in favor of one of them, only the attending physician can individually.

Restrictions on use

Instructions for use indicate that the main limitation to the use of the drug Azithromycin and its substitutes is the individual intolerance of the active component. Contraindications to use: kidney and liver diseases, heart rhythm disturbances.

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It is forbidden to take an antibiotic while taking the following drugs:

  • "Digoxin";
  • "Warfarin";
  • Teldan.

The suspension is prohibited for use by patients under six months of age. Women during the period of bearing a child can use the drug only as directed and under the strict supervision of the attending physician. Women during breastfeeding should refuse the influence of the drug.

Adverse reactions

The drug Azithromycin and its substitutes can negatively affect the body in the form of the following reactions:

  • vertigo, sleep disorder, skin sensitivity disorder, diarrhea, excess gas in the intestines, abdominal pain;
  • tachycardia, chest pain;
  • extremely rare: Botkin's disease, disruption of the intestines, discoloration of the tongue, inflammation of the kidneys, hepatic encephalopathy.

Reviews

Reviews of the antibiotic Azithromycin include most of the positive experiences. It is an effective and inexpensive remedy that can eliminate various infections. Some patients were able to overcome with it a lingering cold, others - an advanced form of pneumonia, others - acute respiratory diseases, pathologies of the genitourinary system.

The opinions of patients focus on the fact that there is no need for multiple daily use of the drug, for a short course of treatment. However, the instructions for use give recommendations to take into account serious limitations. Due to their availability, the medication can be purchased at the pharmacy only with a doctor's prescription.

As a rule, they switch to analogues of Azithromycin due to individual sensitivity to the constituent components. Another reason may be the lack of such a dosage form as an injection.

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