Ascaris In The Blood In Adults And Children, Symptoms, Treatment And Tests

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Ascaris In The Blood In Adults And Children, Symptoms, Treatment And Tests
Ascaris In The Blood In Adults And Children, Symptoms, Treatment And Tests
Video: Ascaris In The Blood In Adults And Children, Symptoms, Treatment And Tests
Video: Diagnostic Features of Intestinal Nematodes 2023, February
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  • Linked immunosorbent assay

    Method essence

  • Blood test
  • Blood test for antibodies

    Results and transcript

  • Symptoms with roundworm in the blood
  • Symptoms of chronic ascariasis
  • FAQ

    • Which analysis is more accurate?
    • What is the probability of error when analyzing for ascariasis?
    • Can ascariasis be asymptomatic?
  • You can defeat parasites!

Ascariasis can give dangerous complications, therefore it is better to diagnose and treat this ailment as early as possible. The main problem is the difficulty of making a diagnosis in the initial stages.

For diagnostic purposes, various tests are carried out for roundworms. In the early stages, roundworms can be found in the blood. Diagnosis of chronic ascariasis is simpler and less costly, since at this stage, eggs of worms can be found in the feces.

What to do in such a situation? To get started, we recommend reading this article. This article details the methods of dealing with parasites. We also recommend contacting a specialist. Read the article >>>



Linked immunosorbent assay

Of all the tests for ascariasis, the serum enzyme-linked immunosorbent assay (ELISA) is considered the most effective. For the analysis, venous blood is needed, in which the presence of antibodies to ascaris is detected.

If we talk about which blood test is better, then ELISA has the following advantages:

  1. The reliability of the technique is 90%;
  2. The disease can be detected at an early stage;
  3. With the help of such a blood test, you can evaluate the effectiveness of treatment and adjust therapy;
  4. Analysis results can be obtained in a couple of days.

Since ELISA requires special equipment, this research method is quite expensive, but its advantages are offset by a few disadvantages.

Method essence

After entering the human body, roundworms inevitably produce antigens against which our immune system produces antibodies. These are specific immunoglobulins such as IgG and IgM. They allow to eliminate the toxic effect of the parasite's waste products on the human body. By the concentration of these immunoglobulins, one can judge not only the presence of the disease, but also the time of invasion and the intensity of the process.

At different stages of the disease in the blood, it is possible to detect specific antibodies of cash A, G and M, as well as antibodies of the general type E and D. Almost on the fifth day of the disease, the amount of IgM class immunoglobulins in the blood increases, and the concentration of IgG antibodies begins to increase only from 21-42 day of illness.



Blood test

The presence of roundworm in blood tests determines whether there is a decrease in blood cells and how significant it is. These are indicators of hemoglobin and erythrocytes. This condition is commonly referred to as anemia. They decrease due to the fact that toxins enter the blood due to the presence of helminths in the body. The study also shows the number of leukocytes, with an increase in the body of parasites, leukocytes also grow. The rate of the indicator is -0-5%. Blood criteria such as eosinophils and ESR are also important.

Norms of other indicators:

  • hemoglobin 120–140 g / l;
  • erythrocytes from 3.5-5.5 million / ml.

However, ascariasis is not the only reason for changes in blood composition. For the diagnosis of ascariasis, this analysis alone is not enough. It goes hand in hand with other studies. It is important that the interpretation of the results is carried out by specialists.

Blood test for antibodies

Another way to check for the presence of helminths in the body is a blood test for antibodies such as IgE and IgG. They appear in people infected with ascariasis. Diagnosis using immunological research at an early stage of ascariasis is relevant. Antibodies show whether the body is infected with helminths located in the large intestine, this analysis allows you to identify the disease in time without allowing it to go into a chronic form.

Blood test for enterobiasis
Blood test for enterobiasis
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Similar studies are prescribed, and when the general analysis shows high leukocytes. Not limited to this, doctors usually conduct a comprehensive examination, relying also on the symptoms and clinical presentation.

But it is this study that allows you to start treatment before complications appear.

Such serologic testing is of limited value in people with immunodeficiency disorders and in infants. Blood is taken from a vein, tested on an empty stomach. For efficiency, it is advisable not to eat fried and fatty foods a day before it, and do not drink alcohol.

The efficiency of the method is up to 95%. In combination with decoding analyzes, clinical blood tests and other measures, it allows the doctor to prescribe the correct therapy.

Results and transcript

The antibody test result can be:

  • Positive indicates the initial stage or already transferred ascariasis.
  • A negative result occurs in the absence of ascaris, an early or, conversely, a late stage of ascariasis.

If in doubt, it is advisable to repeat the study in 2–3 weeks. There are many drugs for ascariasis, but only a doctor prescribes treatment. After the course, you will need to take tests for ascaris again. To determine how effective the therapy was. If necessary, the doctor can prescribe a second course.

Symptoms with roundworm in the blood

The time of the lesion and the severity of the symptoms of ascariasis in each patient are different, and depend on the degree of concentration of the larvae in the body. Helminthic invasion with a small accumulation of parasites may be characterized by a complete absence of any signs.

Symptoms of ascariasis when infected with a large number of worms appear depending on the stage of the disease, they are as follows:

  • mechanical cough, sometimes with blood;
  • slight pain in the right hypochondrium of the chest;
  • shortness of breath with little physical exertion, tachycardia;
  • allergic reactions of varying degrees of intensity (itching, scabies, skin redness, urticaria);
  • fever with joint pain, increased sweating;
  • stomach pain, nausea;
  • lowering blood pressure.

Take a test for ascaris

Symptoms Answer Itching in the anal area Yes Not Dysbacteriosis Yes Not General weakness Yes Not Dry cough Yes Not The appearance of allergic reactions Yes Not Weight loss Yes Not Headaches Yes Not Dizziness Yes Not Increased irritability Yes Not Swelling of the face and eyelids Yes Not

Symptoms of chronic ascariasis

In the late phase of development of ascariasis, most of the characteristic signs are associated with the activity of matured larvae in the small intestine.

The symptoms of chronic ascariasis are as follows:

  • irregular bowel movements;
  • itching at the anus, redness of the skin;
  • cramping abdominal pain, severe vomiting;
  • decreased appetite, sudden weight loss;
  • symptoms of a nervous syndrome: sudden mood swings, poor sleep, nightly grinding teeth, mild convulsions;
  • due to ascariasis, the skin often suffers: abscesses, inflammations, acne appear.

FAQ

Since the analysis is quite expensive, patients have many questions regarding the need for its delivery, effectiveness and other points.

Below is a list of questions with answers to them:

  1. Is this analysis a scam for money? This study allows you to get a reliable result in the first month of infection. In a chronic course, immunodeficiency states, a blood test of newborns, antibodies can be difficult to detect.
  2. What is the most accurate research method? The answer to this question is directly related to the stage of the disease. In any case, a comprehensive study is being conducted.
  3. Are there erroneous results? The margin of error is only 10 percent. The accuracy of the analysis for IgG antibodies is 94%. In case of doubtful results, a clarification is carried out; for this, the blood test is repeated after a month.
  4. Sometimes patients are interested in the answer to the question regarding the disease itself, in particular, can the disease not give symptoms? Indeed, with a slight invasion and at an early stage, the disease is sometimes asymptomatic.

A neglected disease can cause pathologies of the gastrointestinal tract, allergic reactions, intestinal obstruction, obstructive jaundice, pneumonia, pancreatitis and appendicitis. That is why timely diagnosis and treatment is so important, which will help to avoid dangerous complications.

Which analysis is more accurate?

If the primary diagnosis calls into question ascariasis, then the study should be comprehensive, since at different cycles of ascaris development, they can be detected by fundamentally different methods.

What is the probability of error when analyzing for ascariasis?

A positive or negative result in the acute stage of development gives an error of only 10%. In this case, the accuracy of the determination of individual antibodies, for example, IgG to roundworms, is at least 94%. Questionable analyzes to be clarified. About a month after the first study, repeated results are analyzed in dynamics, and when the titer decreases or increases, respectively, a negative or positive conclusion is given.

Can ascariasis be asymptomatic?

At an early stage of the life cycle of ascaris, in particular during migration through the body, especially with a slight lesion, ascariasis is almost asymptomatic.

Ascariasis causes various pathologies: from gastrointestinal to temporary localization organs and allergic reactions. Invasion can cause intestinal obstruction, pneumonia, obstructive jaundice, pancreatitis, appendicitis. Therefore, diagnosis and correct interpretation of the results is so important at all stages of ascariasis.

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