Is It Possible To Determine Worms By Blood Test?

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Is It Possible To Determine Worms By Blood Test?
Is It Possible To Determine Worms By Blood Test?

Video: Is It Possible To Determine Worms By Blood Test?

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Video: What your Blood Test Reveals 2023, February
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  • What worms can be identified in the blood

    • Ascaris
    • Opisthorchiasis
    • Trichinosis
    • Strongyloidosis
  • Blood test for roundworm
  • Analysis for opisthorchiasis in the blood
  • Blood test for trichinosis

    • General analysis
    • Serological method
  • Strongyloidosis blood test
  • You can defeat parasites!

Is it possible to determine worms by blood test? Yes, of course you can. A blood test for helminths is one of the most common, accurate and demanded diagnostic techniques used in pediatric and adult medicine.

It helps to recognize the infection with parasites at the earliest stages, and even when the disease is latent asymptomatic.

What to do in such a situation? To get started, we recommend reading this article. This article details the methods of dealing with parasites. We also recommend contacting a specialist. Read the article >>>

What worms can be identified in the blood

There are several types of tests that can reliably identify the presence or absence of parasites in the body: analysis of feces for helminth eggs, scraping, blood test for antibodies. Also, indicators of a general blood test can indicate the presence of helminths - the patient has increased hemoglobin and ESR.

Ascaris

The primary diagnosis of ascaris infection is made by a doctor. Without examination and questioning of the patient, without taking into account the anamnesis, it is impossible to establish the time and cause of the appearance of worms. Among the methods of diagnosing blood, to clarify the primary diagnosis, there is a serological one.

Ascaris
Ascaris
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Ascaris

This method of laboratory examination of blood serum for the presence of antibodies produced in response to parasitizing helminths: the reaction of indirect hemagglutination, immunofluorescence and enzyme-linked immunosorbent assay (RNGA, RIF and ELISA, respectively) of a high accuracy class.

Opisthorchiasis

As methods of serological diagnosis of opisthorchiasis, ELISA and RPGA are widely used, which make it possible to diagnose the disease at the early stages of the development of the pathological process, before the parasites start laying eggs. At the onset of the disease, these methods are considered the only laboratory diagnostic tools.

Opisthorchiasis
Opisthorchiasis
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Opisthorchiasis

Trichinosis

Determination of specific antibodies to trichinosis antigens is a sensitive and specific method that is widely used in the diagnosis of trichinosis..

Specific antibodies appear 14-15 days after infection and reach a maximum at 4-12 weeks. A negative result may not rule out Trichinella infection early in the infection.

Trichinella
Trichinella
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Trichinella

Strongyloidosis

Usually, strongyloidosis is accompanied by eosinophilia: in most patients, the number of eosinophils in the blood increases from 6 to 15% (in absolute values ​​- 500-1500 cells / μl), but with strongyloidosis against the background of the use of immunosuppressants, eosinophilia may be absent.

Serological tests (blood tests for the presence of antibodies to the parasite, which appear as a result of contact of filariform larvae with the human immune system) are the most sensitive type of research in chronic infection.

Intestinal acne
Intestinal acne
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Intestinal acne

Get tested for worms

Symptoms Answer Itching in the anal area Yes Not Diarrhea Yes Not General weakness Yes Not Dry cough Yes Not The appearance of allergic reactions Yes Not Rapid weight loss Yes Not Headaches Yes Not Dizziness Yes Not Increased irritability Yes Not Shortness of breath Yes Not

Blood test for roundworm

A blood test for ascariasis is a serological study in which specific IgG or IgE antibodies of the IgG or IgE class to ascaris antigens, produced by the host's immunity, are searched for in the blood serum in the presence of larvae and adults of these parasites in the body. At an early stage after infection, the analysis of the level of specific IgE is more informative, after a few weeks - IgG, which begins to be produced later.

The lgg antibody test is indicated in the following cases:

  • preventive goals;
  • if diagnosis is difficult;
  • control of the deworming process;
  • examination of the carrier.

When the results of a general blood test indicate an increased content of leukocytes for no apparent reason, the attending physician conducts a test for antibodies to ascaris antigens.

Moreover, the diagnosis should be done as quickly as possible, since the symptoms of helminthiasis develop very rapidly. These include:

  • muscle pain;
  • dry cough;
  • insomnia;
  • dyspnea;
  • increased temperature;
  • deterioration of immunity, etc.

When donating blood, it is taken from a finger on an empty stomach in the morning. The day before delivery, exclude alcohol from consumption, preferably cigarettes, as well as fatty, fried, salty and smoked foods.

If the analysis shows an increase in the number of leukocytes and a decrease in other red blood cells, then this may be a sign of ascariasis, then tests for roundworms are additionally taken, the blood is checked for the presence of IgG antibodies to roundworm antigens. In this case, blood is taken from a vein on an empty stomach and with the same rules before the procedure.

Analysis for opisthorchiasis in the blood

To date, immunodiagnostics is used very often when opisthorchiasis is suspected. In most cases, an enzyme immunoassay is performed. It can help detect an increase in the concentration of class G and M immunoglobulins.

Gastroenterol
Gastroenterol
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IgM appear immediately after the first contact of the human body with the parasite.

It is recommended to carry out ELISA in 1-2 weeks from the moment of possible infection, since it is at this time that the concentration of antibodies is maximum. IgG appear a little later: at 3-4 weeks of illness.

A healthy person who has never had opisthorchiasis has no antibodies. The sensitivity of this test is determined by the course of the disease. If there is an acute period, the sensitivity is 100%. If the disease is chronic, then this figure is about 70%. As the disease progresses, the antibody titer decreases.

This is due to the formation of circulating immune complexes. Sometimes during ELISA, false positive results are observed. This can be facilitated by the presence of liver diseases, allergic diseases in a person.

Blood test for trichinosis

There are two methods of blood analysis for trichinosis: general research and serological diagnosis.

General analysis

In human blood, there are several types of white blood cells - leukocytes - each of which has its own function. Eosinophils are a type of white blood cell that is involved in allergic reactions. During trichinosis, accompanied by allergies, their blood levels are very high. This is detected using a general blood test.

Serological method

It is the detection of antibodies that are produced in the patient's body in response to the introduction of parasites. To do this, use the reaction of blood with antigens obtained from Trichinella larvae.

Types of serological diagnostics for trichinosis:

Abbreviation Decoding The essence
RSK Complement binding reaction If there are antibodies in the patient's blood, then they combine with the antigen and attach to themselves a compliment molecule - a special substance that participates in immune reactions. In this case, the reaction will be considered positive.
RNGA Indirect hemagglutination reaction It is based on the ability of erythrocytes to stick together when there is an antibody and antigen on their surface.
ELISA Linked immunosorbent assay A reaction is carried out between antibodies and antigens. Special enzymes serve as a label that allows you to evaluate the result.
REEF Immunofluorescence reaction There is a special label in the material, which leads to a glow after the antibody reacts with the antigen.
REMA Reaction of enzyme-labeled antibodies. The result can be assessed using a special label, which is an enzyme.

Strongyloidosis blood test

In most cases, the disease is diagnosed at a late stage, based on the results of a serological test for strongyloidosis. According to the results of blood tests, it is impossible to diagnose the disease, they act only as additional information to the results of feces tests.

With strongyloidosis, there is a significant increase in the level of eosinophils (5% or more), as well as an increase in the erythrocyte sedimentation rate (ESR). A significantly abnormal level of eosinophils indicates an early stage of the disease, as well as an allergotoxic form of the disease.

In the presence of specific antibodies in the blood, an immune compound occurs, to which a special enzyme is attached, which stains the formed complex. The glow intensity is determined by a special test system.

Deadlines 7-9 days
Synonyms (rus) Antibodies of specific immunoglobulin G against intestinal acne
Synonyms (eng) Autoimmune IgG to Strongyloides stercoralis
Analysis methods Semi-quantitative enzyme immunoassay
Preparation for research The analysis is carried out in the morning on an empty stomach.

At least 8 hours should pass from the last meal.

Avoid alcohol intake at least 24 hours before taking biomaterial.
It is not recommended to donate blood for serology after fluorography, X-ray, physiotherapy procedures.
Biomaterial and methods of its collection Blood selection is made from a vein.

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