Toxoplasmosis Of The Brain: With HIV, Symptoms, Treatment And Consequences

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Toxoplasmosis Of The Brain: With HIV, Symptoms, Treatment And Consequences
Toxoplasmosis Of The Brain: With HIV, Symptoms, Treatment And Consequences

Video: Toxoplasmosis Of The Brain: With HIV, Symptoms, Treatment And Consequences

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Video: Bugs in the Brain - HIV and Toxoplasmosis 2023, February
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Page content

  • How does the brain damage occur with toxoplasmosis?
  • Symptoms of toxoplasmosis of the brain
  • Toxoplasmosis of the brain in HIV
  • Treatment of toxoplasmosis of the brain
  • Diagnostics
  • Consequences of the disease
  • You can defeat parasites!

Toxoplasmosis of the brain is a parasitic disease caused by Toxoplasma gondii. The microorganism is one of the simplest. In appearance, they are similar to the shares of an orange.

The parasite is capable of infecting all internal organs and systems: the brain and spinal cord, liver, heart, spleen, etc. In many cases, toxoplasmosis is chronic and difficult to treat.

What to do in such a situation? To get started, we recommend reading this article. This article details the methods of dealing with parasites. We also recommend contacting a specialist. Read the article >>>

Toxoplasma gondii
Toxoplasma gondii
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Toxoplasma gondii

How does the brain damage occur with toxoplasmosis?

The disease can be congenital or acquired. In the first case, infection with toxoplasma during the prenatal period, from the mother to the fetus. In the second case, pets, namely cats, most often infect a person.

They are intermediate hosts for parasites. Only in them, Toxoplasma is able to form oocysts (spore, egg), which invade the human body.

The spores of the parasite are excreted from the infected cat into the external environment with feces, urine, saliva and milk. Domestic cats in some cases become a "victim" of a situation when the owners themselves bring toxoplasma into the house on the soles of their shoes, or feed the pets with contaminated meat.

Also, a person can become infected by eating raw meat with pathogens.

This is what an affected brain looks like
This is what an affected brain looks like
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This is what an affected brain looks like

Symptoms of toxoplasmosis of the brain

Pathology mainly develops against the background of weakened immunity. People in good health may not have symptoms. Only laboratory tests will show the presence of antibodies to the pathogen.

In people with poor health, clinical manifestations occur 2 weeks after infection. It should be noted that toxoplasmosis of the brain is recorded in very rare cases.

The clinical picture initially consists of general weakness, pain in muscles and joints. After a while, the acute stage develops rapidly:

  • The body temperature rises.
  • Lymph nodes become inflamed.
  • A rash appears all over the body. As an exception, skin abnormalities do not occur on the palms, feet, and hairy parts of the body.
  • Headache develops from intoxication.

In the future, the symptoms of hepatitis, nephritis, myocarditis, etc. are added. Then meningitis, encephalitis, meningoencephalitis develops.

Typical signs of brain damage: loss of memory and orientation, seizures, paresis, impaired coordination of movements and speech, visual impairment. Subsequently, the acute form is replaced by a chronic course.

A sluggish disease has periods of remission. The chronic form is characterized by intoxication of the body, low-grade fever, pain in the joints and muscles.

The patient has confusion, irritability. From the gastrointestinal tract, pain in the abdomen, bloating, and upset stools are noted.

After migration through the human body, parasites form pseudocysts in organs. Subsequently, they are mineralized, and in patients with palpation of muscles, calcifications (dense formations) can be felt.

Toxoplasmosis is especially dangerous during pregnancy. If the mother is infected, the death of the fetus is possible in the first trimester, and at a later date it causes severe destructive damage to the child's brain.

Toxoplasmosis of the brain in HIV

The cerebral form of the disease is common among people with immunodeficiency syndrome. In patients with HIV status, the infection is particularly severe. In this case, toxoplasmosis becomes the cause of death.

Basically, the pathology manifests itself in the form of meningoencephalitis with foci of extensive brain damage.



Treatment of toxoplasmosis of the brain

The chronic form is difficult to treat. Basically, immunomodulatory drugs and vitamin complexes are prescribed. From medicines used Levamisole, Cerebrolysin (nootropic agent) and other drugs.

The acute form is stopped with the help of drugs: Pyrimethamine + Sulfadiazine, Trimethoprim with Sulfamethoxazole, Lincomycin hydrochloride, Rovamycin and others. The doctor prescribes the treatment regimen and dosage with reference to the patient's condition, individual characteristics, etc.

Levamisole
Levamisole
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Diagnostics

The symptoms of toxoplasmosis are similar to other diseases. To establish an accurate diagnosis, laboratory tests are prescribed. Blood is taken for serological analysis. Thus, specific antibodies to Toxoplasma are detected.

To determine the data on changes in the brain, MRI and computed tomography are used. The data obtained are compared with each other.

Consequences of the disease

In the chronic form, there are almost no consequences for human health. The prognosis for recovery is favorable. The consequences of HIV are extremely unfavorable and fatal.

In many ways, the consequences of toxoplasmosis depend on the promptness of contacting medical institutions. Attempts to treat with folk remedies only aggravate the infection and lead to serious consequences.

To prevent infection, it is necessary to monitor personal hygiene, thoroughly wash fruits and vegetables, and avoid eating raw and poorly processed meat. If there are cats in the house, it is important to monitor their health so that they do not become carriers of toxoplasma and other parasites.

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