Toxoplasma Igg Antibodies: What Does It Mean If A Positive Result

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Toxoplasma Igg Antibodies: What Does It Mean If A Positive Result
Toxoplasma Igg Antibodies: What Does It Mean If A Positive Result

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Video: Toxoplasma Igg Antibodies: What Does It Mean If A Positive Result
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  • Igg antibodies to toxoplasma discovered - what does it mean
  • Toxoplasmosis decoding table
  • Positive results
  • What if Toxoplasma IgG antibodies are not detected
  • Toxoplasma IgG avidity
  • What does Toxoplasma IgM mean?
  • IgG antibodies to toxoplasma in pregnancy
  • Where to get tested in Moscow
  • You can defeat parasites!

Toxoplasmosis is one of the most common human diseases. This is due to a high susceptibility to protozoal parasites and an increased chance of infection from domestic cats. The disease is extremely rarely characterized by an acute course, but it is better to know in advance about its symptoms and preventive measures.

Igg antibodies to toxoplasma discovered - what does it mean

IgG and IgM are the main keys to deciphering the enzyme immunoassay for toxoplasmosis. There are various combinations of results that help to know about the presence or absence of immunity to the parasite, the likelihood of primary or secondary infection. In the venous blood, during the delivery of tests, immunoglobulins of the M and G classes can be detected, which help to make a diagnosis.

What to do in such a situation? To get started, we recommend reading this article. This article details the methods of dealing with parasites. We also recommend contacting a specialist. Read the article >>>

Since in most cases the disease is asymptomatic, it is necessary to pass tests to detect antibodies. Usually, when planning a pregnancy, a woman also donates blood to detect infection, since toxoplasmosis can adversely affect the development of the fetus, which still has a too weak immune system, she will not be able to suppress the infection.

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Toxoplasma

Get tested for worms

Symptoms Answer Itching in the anal area Yes Not Dysbacteriosis Yes Not General weakness Yes Not Dry cough Yes Not The appearance of allergic reactions Yes Not Weight loss Yes Not Headaches Yes Not Dizziness Yes Not Increased irritability Yes Not Swelling of the face and eyelids Yes Not

Toxoplasmosis decoding table

Index Description
IgM-, IgG- No immunity.
IgM-, IgG + Chronic wearing of Toxoplasma, recovery. No therapy required.
IgM +, IgG- Acute form, treatment required.
IgM +, IgG + Exacerbation of toxoplasmosis, treatment is necessary.

Positive results

Immunoglobulin G speaks of prolonged circulation of antibodies in the blood plasma. The absence of IgM antibodies and the presence of G glycoproteins is considered a favorable result - a sign that the body has already encountered Toxoplasma and has developed immunity to it, which protects against re-infection.

Positive in such an analysis is the ability of IgG antibodies to protect the child who is in the womb. Glycoproteins provide protection for the woman and the unborn child.

When positive IgM is noted in the assays along with IgG antibodies, two options are considered:

  • a sign of a primary infection that lasts about a month;
  • reactivation of toxoplasmosis (extremely rare).
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In this case, it is required to determine the avidity (the strength of the bond between the antigen and the antibody), the risk to humans.

If the analyzes indicate IgM positive, and IgG negative - a sign of primary infection, with the excluded laboratory error. In this case, the risk for a person is not high, because after a while, under the influence of antibodies, the body will begin to produce IgG markers.

If the patient has acute symptoms, antibiotics are prescribed, which can affect intracellular microorganisms.

Toxoplasma reactivation is rare. Maybe it is due to a weakened immune system due to a combination of stress with systemic diseases, taking medications that weaken the body's defenses.

To eliminate this condition, expectant tactics are used - the body must cope with the infection itself. In the presence of complications and inflammatory processes, it is necessary to use medical methods. It is forbidden to take glucocorticosteroids, immunostimulants, antiprotozoal drugs are used.

What if Toxoplasma IgG antibodies are not detected

If the IgG indicator in the body is positive, it means that the immune system has already fought with the pathogen and the likelihood of protection against secondary infection increases. However, such an analysis may indicate a recent primary infection.

To make an accurate diagnosis, the doctor needs to analyze the IgM indicators - they appear only during an exacerbation of the disease. If their indicator is positive, then the person has been infected recently. If IgM is negative, there is no infection, there is no danger.

If both antibody readings are positive, there is a serious risk to fetal health.

If the IgG test results are negative (they are absent in the body), the person must adhere to preventive measures that protect against infection, especially during pregnancy.

This analysis suggests that the body lacks antibodies that provide protection against toxoplasmosis.

Toxoplasma IgG avidity

Avidity in% Avidity degree Decoding the results
= or <40 Low avid Sign of acute primary infection. If such indicators are diagnosed during pregnancy, a PCR test is required.
41-59 Transitional Sign of unreliable results. It is necessary to pass repeated tests after 14 days.
> or = 60 Highly avid Such indicators indicate a developed immunity to Toxoplasma. It is also possible a chronic course of the disease or a person is its carrier.

What does Toxoplasma IgM mean?

When the body encounters an infection, IgM antibodies begin to be produced in the blood, after a while IgG antibodies. At primary infection, IgM antibodies are positive and IgG antibodies are negative. With negative IgM and positive IgG, we can talk about the developed immunity to Toxoplasma.

IgG antibodies to toxoplasma in pregnancy

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Toxoplasmosis refers to diseases that negatively affect the development of the fetus. If a woman's tests do not contain IgG antibodies, then her body will not be able to protect the embryo from the intracellular parasite.

The immune system of an adult is able to cope with infection on its own, but the fetus does not yet have full protection, so it is susceptible to infection.

Toxoplasmosis leads to the development of various pathologies of the unborn child:

  • thrombocytopenia;
  • hydrocephalus, microcephalus;
  • chorioretinitis;
  • calcification;
  • liver disease;
  • poor intrauterine development, lack of development after childbirth;
  • inflammation of the eyes, which ends with anophthalmia.

In 10-15% of cases, the lack of treatment for toxoplasmosis during pregnancy ends in premature birth, fetal death. The most dangerous is the impact of infection in the first trimester - during this period, the development of all organs begins. If infection occurs during this period, doctors prescribe an abortion.

Toxoplasma therapy requires an integrated approach using increased doses of folic acid (5 mg per day). This approach reduces the negative effects of medications, eliminates disorders of the nervous system, which suffers from the pathogen and medication.

Where to get tested in Moscow

You can get tested for toxoplasmosis at:

  • Moscow, st. metro Kashirnskaya, st. Moskvorechye, 1. in the medical laboratory of genetic engineering systems "LAGIS".
  • Moscow, Yeniseiskaya 37 in the clinical diagnostic laboratory "KDL".

Avoiding infection with infections is quite simple, you just need to adhere to basic hygiene rules, regularly visit a medical facility to check your general health and take tests for various pathogens.

When planning a pregnancy, it is imperative to pass all the necessary tests, because toxoplasmosis negatively affects the development of the fetus.

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