Toxoplasma Igg Antibodies Detected: What Does It Mean

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Toxoplasma Igg Antibodies Detected: What Does It Mean
Toxoplasma Igg Antibodies Detected: What Does It Mean

Video: Toxoplasma Igg Antibodies Detected: What Does It Mean

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Video: Antibody Testing: IgG and IgM explained 2023, February
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Knowing what igg toxoplasmosis positive means is, first of all, necessary for women planning pregnancy. Timely diagnosis of toxoplasmosis is a guarantee of healthy fetal development.

Content

  • 1 What is toxoplasmosis
  • 2 About the pathogen
  • 3 Infection in the human body
  • 4 Toxoplasmosis enzyme immunoassay
  • 5 As evidenced by the diagnostic results

    • 5.1 Igg positive and igm negative
    • 5.2 Igg negative and igm positive
    • 5.3 Igg positive and igm positive
    • 5.4 Igg negative and igm negative
  • 6 Examination of a born baby
  • 7 Congenital form
  • 8 Conclusion

What is toxoplasmosis

This is an infectious disease. They can hurt not only a person, but also certain animals that have a disposition for this.

The disease is caused by the parasite Toxoplasma gondii. You can get infected with toxoplasmosis:

  • after direct contact with animal feces;
  • if there is meat from an animal (infected);
  • blood transfusion;
  • from mother to child through the placenta.

The most severe form is congenital toxoplasmosis. Its main symptoms are:

  • enlarged lymph nodes;
  • heat;
  • persistent eye pain;
  • frequent fatigue;
  • poor vision (blurry picture).

About the pathogen

Toxoplasma gondia is a unicellular parasite with a difficult life cycle. It is in the body of the cat that the parasite's puberty takes place, that is, the animal is the final host. Pets are infected by pigeons, mice, and other infected animals.

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After reproduction, Toxoplasma enters the outside world along with the pet's feces. A person becomes infected with Toxoplasma through contact with feces and acts as a temporary host.

Infection in the human body

The concept of the essence of the disease begins with the simplest. First of all, you need to figure out how the human body behaves in the presence of any kind of infection.

As soon as the parasite enters the host's bloodstream, the immune system recognizes it as a substance that carries signs of genetically foreign information (foreign body), and begins to fight it, producing at. Their action is directed against a certain type of parasitic organism. Immunoglobulin is specific only to a certain antigen and, when recognized, binds to it.

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Immunoassay for toxoplasmosis

In other words, it is also called ifa. This short abbreviation, which stands for enzyme-linked immunosorbent assay for the determination of igg and igm antibodies to toxoplasmosis in blood serum. What is the characteristic of this analysis?

The research is carried out exclusively in laboratory conditions. Specialists with the help of a biochemical reaction determine whether there are immunoglobulin proteins in the patient's blood. They are produced by the body to further fight antigens.

With the help of the bloodstream, antibodies that were previously produced are carried to all organs. When they find their type of infection, they begin to bind with them, forming a complex. After a while, the harmful substances are completely neutralized.

What the diagnostic results indicate

  1. igg with a "+" sign and igm with a "-" sign.
  2. igg with a "-" sign and igm with a "+" sign.
  3. igg with "+" sign and igm with "+" sign.
  4. igg with a "-" sign and igm with a "-" sign.

If igg to toxoplasma serum has been identified, this may mean one of the following options.

Igg positive and igm negative

This result may mean that the human body is resistant to disease. He copes with the causative agent of toxoplasmosis without any problems. The combination of am when found in the blood of children, adults and pregnant women is evidence that this group of people does not need further research. However, if the diagnosis was carried out in the first weeks of pregnancy, in addition to this, tests must be taken to determine if there is Toxoplasma DNA in the blood and urine - by the polymerase chain reaction (PCR) method.

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Igg negative and igm positive

This conclusion confirms the primary stage of infection of the body with Toxoplasma. Women who are carrying a child during this period need to be diagnosed, since there is a possibility that cysts can enter the fetus.

In this situation, it is recommended to do the following - to investigate whether there is DNA of parasites in the blood and urine by PCR. After 13 days, undergo an examination again for the presence of am (igg and igm). The second time, igg comes out positive. If igg is in the body with a "+" sign and there is DNA, the doctor selects the appropriate treatment. Failure to detect DNA indicates that the igm test was mistakenly considered positive as a result. In this case, no treatment is required.

Igg positive and igm positive

What does it mean if Toxoplasma igg antibodies are detected during examination? The probability of the primary stage of infection is high. It is important not to forget that igm has the property that its “+” sign remains for several years.

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Igg negative and igm negative

The likelihood of infection is excluded. But the result does not exclude additional examination for women carrying a child. They are included in the risk group and examined every trimester of pregnancy. The examination is carried out between the 22nd and 24th week of pregnancy and just before childbirth.

If seroconversion is present, amniocentesis may be needed to detect infection. Further, treatment is prescribed for both the mother and her baby.

Examination of a born baby

The result of the analysis of the baby depends on the result of the examination of his mother. If igm was positive in both cases, the diagnosis is confirmed by the attending physician.

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The latent and chronic form of the disease in a newborn child may not be revealed. However, this is possible in cases where the infection occurred in the first or third trimester of pregnancy. The presence of infection is determined according to the dynamics of igg antibodies. To do this, you need to find out the level of igg in the mother's blood.

Congenital form

The disease passes from mother to baby through the embryonic organ during gestation. If infection occurs early in pregnancy, it can cause fetal death. The likelihood of a dead baby is not excluded. It is very difficult for infected children to tolerate toxoplasmosis. They often die immediately after birth.

Classic symptoms in children with congenital toxoplasmosis:

  1. Inflammation of the retina, in scientific terms - chorioretinitis. As a result, blindness develops.
  2. Jaundice.
  3. Deafness.
  4. Red nodules on the skin.
  5. Change in the size of the spleen and liver.
  6. Head too small or too large.
  7. Delayed development.

Conclusion

Antibodies with class G (igg) indicate the presence of a dangerous disease in the body - toxoplasmosis. Its symptoms depend on how old the patient is. This can be a newborn, a pregnant woman, or a young man. Parasites in the human body are able to act in different ways on the body, gradually destroying its vital organs.

In order not to risk the health of the baby, it is necessary to be examined in time and listen to all the doctor's recommendations. And of course, do not forget about hygiene, because this is the only way to avoid infection.

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