Giardia Tablets In Adults: How To Choose Effective

Table of contents:

Giardia Tablets In Adults: How To Choose Effective
Giardia Tablets In Adults: How To Choose Effective

Video: Giardia Tablets In Adults: How To Choose Effective

Отличия серверных жестких дисков от десктопных
Video: Giardiasis 2023, January
Anonim

Giardiasis is a parasitic disease affecting the gastrointestinal tract of animals and humans, transmitted through contaminated food and water or through direct contact with an infected person (fecal-oral). In addition, there is the possibility of transmission during anal or oral sex.

Content

  • 1 Clinical signs
  • 2 Treatment

    • 2.1 Entisol
    • 2.2 Tinidazole
    • 2.3 Ornidazole
    • 2.4 Vermox
  • 3 Prevention

The causative agents of the disease are unicellular intestinal flagellates Giardia intestinalis, which arise in a vegetative (trophozoite) and cystous (cyst) form.

The treatment of giardiasis today is not as complicated as it used to be, and there are various drugs and tablets for lamblia in adults on the market. Consider what to guide you when choosing a treatment.

Clinical signs

G. intestinalis is the originator of an alimentary diarrheal disease known as giardiasis. Despite the massive conclusions of the analyzes, it does not necessarily come to pathological changes. Most infections are either asymptomatic or subclinical. Only 10% of those infected have clinical manifestations

The acute stage of giardiasis has a short course (3-4 days) and often mimics acute viral enteritis, bacterial dysentery or other bacterial food poisoning, acute intestinal amebiasis or diarrhea caused by toxigenic strains of E. coli.

The incubation period for the acute phase is 12-20 days. Manifested by sudden diarrhea, loss of appetite, nausea, vomiting, and increased flatulence. The stool is light, watery, with a strong odor, containing a large amount of fat (greasy appearance) and mucus, without blood, cellular elements and remnants of worms.

Image
Image

The subacute and chronic phase is manifested by pressing pain in the epigastrium and hypochondria, especially after eating. Diarrhea alternates with constipation, and children have secondary anemia and slow weight gain.

After a few weeks, spontaneous healing can be achieved. Sometimes the disease persists for several months or even years, turning into an asymptomatic form associated with the carriage of cysts.

In addition to the intestinal form of giardiasis, a hepatobiliary form can be demonstrated (in 50% of cases). It manifests itself in the form of acute or chronic cholecystitis. With severe damage to the intrahepatic bile ducts and liver parenchyma, jaundice and hepatomegaly may develop.

Treatment

In the treatment of lamblia tablets, a popular medicine is Metronidazole (Flagil), which is taken in adults in a dose of one tablet (250 mg) 3 times a day. The therapeutic course is 10 days. The recommended dosage for children is 5 mg / kg three times a day. Duration - 5-10 days.

An alternative treatment is Ornidazole (Avrazor), which is taken twice a day, 500 mg. The therapeutic course is 5-10 days.

If the treatment with the above drugs does not show efficacy, Tinidazole (Fazizin) 2 g can be used once (children - 50-75 mg / kg once).

The mechanism of action of these drugs for giardiasis is the effect on the enzyme process of the parasite, which causes its destruction. The effectiveness of therapy is monitored by microscopic examination 2 weeks after its completion.

Image
Image

Entisol

Entisol is a medicine that belongs to the antibiotics of the nitroimidazole group. The active substance of the drug is a compound metronidazole.

  1. Principle. Metronidazole penetrates bacterial cells, attacks their cellular enzymes and damages the addition of bacterial DNA. A good effect is achieved with anaerobic bacteria that do not need oxygen for life.
  2. Application. Entisol kills various anaerobic bacteria and is effective against some protozoa, in particular G. intestinalis. Women can use the drug to treat deep pelvic inflammation and gynecological infections (both bacterial in nature and those caused by protozoa). It is effective in the treatment of diverticulitis and pseudomembranous colitis, it is suitable for intestinal diseases of an inflammatory nature. In combination with other antibiotics, it is suitable for re-treatment of infectious inflammation of the stomach caused by Helicobacter Pylori.
  3. Dosage. Depends on the recommendations of the attending physician. The standard dose of the drug in tablet form for an adult is 250-500 mg 2-4 times a day. The dosage is strictly individual. Also, the medicine is available in the form of a solution for injection and vaginal tablets.
  4. Side effects. The most common side effects of drugs containing metronidazole include digestive problems such as nausea, vomiting, and diarrhea. Polyneuropathy associated with limb tingling and allergic reactions has also been reported.
Image
Image

Tinidazole

It is advisable to consult a doctor before using this drug. It is important to find out if you have had any previous allergic reactions to its active ingredient metronidazole and / or to any other medications.

While taking the drug and for at least 3 days after the end of the therapeutic course, alcohol should be excluded.

  1. Side effects. Rarely, allergic reactions may occur as a result of taking tinidazole. In case of manifestations such as rash, shortness of breath, swelling of the face, you should immediately consult a doctor.
  2. Other side effects of the drug are represented by the following phenomena:
  • convulsions;
  • fever;
  • influenza manifestations.

If these symptoms occur, you should consult your doctor about changing treatment.

Dosage:

  • adults - 2 g / day, taken with food;
  • children from 3 years old - 50 mg / kg of body weight (but not more than 2 g) once a day, taken with food;
  • the medicine is not recommended for children under 3 years old.
Image
Image

Ornidazole

The drug is easily absorbed from the gastrointestinal tract, the bioavailability of the drug reaches 90%. The maximum concentration occurs up to 1.5-2 hours. 60% is excreted in the urine, 20% - with feces in the form of metabolites, unchanged - about 5-6%.

Dosage:

  • adults and children weighing more than 35 kg - 1.5 g one time (preferably in the evening);
  • children weighing up to 35 kg - 40 mg / kg one time.

The therapeutic course is 1-2 days.

Vermox

Vermox is a broad-spectrum drug that also affects G. Intestinalis.

Image
Image

The dosage and method of administration are as follows.

  1. Adults: Although good results have been shown with lower doses, the recommended dose leading to a complete cure is 2 x 5 ml oral suspension in the morning and evening for 3 consecutive days. Even at such a high dosage, unwanted side effects are rare.
  2. Children: 1 x 5 ml oral suspension 2 times a day for 3 consecutive days.

Treatment does not require adherence to any special regimen, dietary changes or the use of laxatives.

The drug is not recommended for children under 1 year of age

Image
Image

Prevention

Preventive measures include adherence to the following rules.

  1. Strict adherence to the principles of personal hygiene.
  2. Adherence to eating habits (in areas with low levels of hygiene, do not drink water from unknown sources, eat raw vegetables and fruits, unprocessed foods; do not buy food from street vendors).

Popular by topic