The Drug Sodium Thiosulfate 30% (Sodium Thiosulfate): Instructions For Use

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The Drug Sodium Thiosulfate 30% (Sodium Thiosulfate): Instructions For Use
The Drug Sodium Thiosulfate 30% (Sodium Thiosulfate): Instructions For Use

Video: The Drug Sodium Thiosulfate 30% (Sodium Thiosulfate): Instructions For Use

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Video: Sodium Thiosulfate : Properties 2023, February
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Preparation of Sodium thiosulfate 30% (Sodium thiosulfate): instructions for use

Sodium thiosulfate 30 belongs to the group of drugs with detoxification action. At the same time, this tool exhibits other properties. It is distinguished by a narrow area of ​​use. Despite the fact that the drug interacts with highly toxic substances, there are few contraindications to its use.

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Sodium thiosulfate 30 belongs to the group of drugs with detoxification action.

Pharmacological properties

The main function of sodium thiosulfate is to eliminate the cause, and at the same time the symptoms of a pathological condition provoked by toxic substances.

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Sodium thiosulfate eliminates the causes and symptoms of a pathological condition caused by toxic substances.

The agent is active in case of poisoning with heavy metals, some poisons (cyanides). Structurally, sodium thiosulfate is a sodium salt.

The principle of operation of sodium thiosulfate when interacting with various toxic substances is similar. However, as a result, different compounds are formed.

For example, when interacting with cyanides, thiocyanates are released. If heavy metals have entered the body, under the influence of the drug in question, their activity is inhibited, since non-toxic sulfides are formed. Thanks to these processes, the poisoning is neutralized.

Another feature is the anti-edema effect. The desired result in a pathological condition is achieved by intensive excretion of fluid (diuretic effect).

At the same time, the drug also exhibits an antiparasitic effect. The drug has a detrimental effect on harmful microorganisms in the intestines, since it is used as a disinfectant. In addition, with the help of the drug in question, scabies is treated. In this case, the active substance decomposes into different components: sulfur and sulfur dioxide, which is facilitated by an acidic environment. As a result, the shell of subcutaneous mites, the offspring of these parasites (larvae and eggs), is damaged.

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The drug has a detrimental effect on harmful microorganisms in the intestines.

In addition, when injected into the body, the drug helps to reduce the intensity of inflammation. It is allowed to be used during the recovery phase for burns. Another property of the agent in question is the ability to eliminate negative manifestations in case of an overdose with lidocaine. The medicine in this case acts as an antidote.

Release form

The drug can be purchased in the form of a solution for intravenous administration, oral administration and external use. Only sodium thiosulfate is included. The drug is produced in ampoules of 10 ml. Their number in a package is 10 pcs. 1 ampoule contains 3 g of active substance.

What is sodium thiosulfate prescribed for?

The drug is recommended for use in the following pathological conditions:

  • poisoning with arsenic, mercury, lead, hydrocyanic acid, bromine;
  • ingestion of salts of hydrocyanic acid, iodine;
  • overdose with lidocaine;
  • parasitic diseases, for example, scabies, sometimes the drug is prescribed as an aid in case of infection with worms;
  • alcohol poisoning;
  • arthritis;
  • lupus erythematosus;
  • neuralgia;
  • allergic manifestations.
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The drug is recommended for use in lupus erythematosus.

How does sodium thiosulfate work on the human body?

The medicine is intended for intravenous administration, oral administration. When an active ingredient enters biological fluids, it circulates, binding with toxic substances. The advantage of this drug is the high rate of elimination from the body.

So, the duration of the half-life is 0.65 hours. The excretion of the drug is made during urination. The active ingredient (sodium salt) does not have a negative effect on the body, since it is not a toxic substance.

Overdose

There is no information on the occurrence of side effects in cases where the dose of the drug is increased. This is due to the fact that the substance does not have a toxic effect on the body. There is no need for an uncontrolled increase in the amount of the drug. It is characterized by sufficient effectiveness when using the recommended doses.

Method of using sodium thiosulfate

The treatment regimen differs not only in the method of drug delivery into the body, but also in the type of disease, pathological condition. The duration of the course of therapy is determined individually. When calculating the dosage, the degree of damage to the body is taken into account.

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In case of poisoning, sodium thiosulfate should be administered intravenously.

In case of poisoning

When highly toxic substances enter the bloodstream, it is required to inject 5-10 ml of solution. The drug is administered intravenously. If cyanide has entered the body, it is recommended to increase the dose of the agent to 50 ml. In these cases, it is important to use only a solution with an active substance concentration of 30%.

To cleanse the body

In order to accelerate the elimination of toxins, decay products and the vital activity of parasites, it is recommended to take the medicine orally - no more than 3 g of the main component. A solution is prepared, the concentration of the active substance is 10%. The product can be diluted with clean boiled water (room temperature) or sodium chloride solution (0.9%).

The drug in such an amount is recommended to be taken 2 times a day: morning and evening. The duration of the course of cleansing the body is 10-14 days.

For allergies

An injection is recommended to remove toxins. 5-10 ml of the product is enough. If pronounced signs of an allergic reaction appear on the skin, it is permissible to use the drug externally. Instructions:

  • the skin in the affected areas is cleansed, but it is recommended to use baby soap for this (do not use perfumed cosmetics, such as shower gel);
  • the drug is applied to dry outer covers;
  • upon drying, the substance crystallizes;
  • then the leather is processed again;
  • after the drug has dried, a solution of hydrochloric acid is applied (concentration 6%).
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If the drug was used externally, then contact with any liquids must be excluded.

If this drug was used externally, then contact with any liquids must be excluded. You should not wet the skin treated with the drug for 2-3 days.

The treatment regimen is the same as for cleansing the body. However, it is not recommended to take the drug in question for a long period, since in this case the risk of hypovolemia increases (the volume of circulating blood decreases). This pathological condition is eliminated by increasing the daily amount of fluid.

For the treatment of female diseases

The drug is used as part of complex therapy for anovulation. In this case, physiotherapy is prescribed, in particular, electrophoresis. In this case, Actovegin and Nicotinic acid are used. These products can cause allergies. To stop negative manifestations, the drug in question is added to the therapy regimen.

The drug can be used for developing ovarian cysts. In this case, the agent in question is recommended to be used together with NSAIDs. As a result, the symptoms of inflammation are relieved more intensively.

Sodium thiosulfate 30% is used as part of complex therapy for anovulation
Sodium thiosulfate 30% is used as part of complex therapy for anovulation

Sodium thiosulfate 30% is used as part of complex therapy for anovulation.

The drug is often used for developing ovarian cysts
The drug is often used for developing ovarian cysts

The drug is often used for developing ovarian cysts.

Sodium thiosulfate also has anti-inflammatory properties in endometriosis
Sodium thiosulfate also has anti-inflammatory properties in endometriosis

Sodium thiosulfate also has anti-inflammatory properties in endometriosis.

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The drug is often prescribed as part of complex therapy for female genital tuberculosis. In this case, the substance exhibits anti-inflammatory properties. The drug has a similar effect in endometriosis.

With psoriasis

The medicine can be used in any way: intravenously, orally, externally. The first of the options is suitable only for severe complications against the background of developing psoriasis. Oral administration helps to cleanse the blood, eliminate waste products and toxins from the body. Thanks to this, it is possible to suppress the increase in the lesion focus.

However, the most effective is the treatment regimen based on the treatment of the external integument. In this case, a more concentrated solution (60%) is prepared. Compresses are recommended. The frequency of use of the product is 2-3 times a day. The duration of the course of therapy is determined in each case separately.

With scabies

The principle of treatment for this disease is the same as for allergies. It is possible to stop the symptoms of scabies and block the mechanism of its development by external application of the drug. This is due to the fact that the causative agent of the disease (subcutaneous mite) lives in the structure of the skin. Taking the solution orally or injecting it into a vein will not provide the desired result.

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For weight loss, the agent in question is used for 10 days.

Slimming

At the initial stage, the agent exhibits a laxative effect. In addition, thanks to this drug, the intestines are cleansed. At the same time, decay products and toxins are removed from the body. All of these factors contribute to weight loss.

However, a positive result against the background of the use of the drug in question can be obtained only if in parallel the patient adheres to the diet, introduces sports training into his daily routine. Therapy scheme:

  • the drug is taken once a day;
  • the solution is prepared as follows: the contents of 1 ampoule are mixed with water (250 ml) and drunk;
  • the duration of treatment is 10 days.

Contraindications

The drug is not used in some cases:

  • intolerance to sodium salt;
  • diarrhea, because at the initial stage of treatment in many patients, the stool becomes liquid, which can aggravate the problem;
  • severe liver damage.
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The drug is not used in case of severe liver damage.

Side effects

Negative manifestations rarely develop, only in cases when the sensitivity of the patient's body is increased. As a result, systemic reactions to the drug in the form of an allergy appear, but the symptoms are mild, since the drug in question is not characterized by toxicity.

In addition, the patient may experience local signs: rash, itching, burning, induration at the injection site. The drug affects the work of the digestive tract. This softens the stool, but this symptom disappears soon after starting treatment. Long-term therapy can cause a decrease in blood volume in the body.

Application during pregnancy and lactation

There is not enough information about the mechanism of action of the drug on the fetus. This means that it can be used during pregnancy only for health reasons, when the positive effects exceed the possible harm in terms of the intensity of manifestation.

It is not known whether the substance passes into the mother's milk. For this reason, you should refrain from using the drug during lactation.

Application in children

The drug is not used in the treatment of patients under 18 years of age. This is due to the lack of information about its effect on the growing organism.

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The drug is not used in the treatment of patients under 18 years of age.

Interaction with other medications

The drug in question cannot be combined with such compounds:

  • nitrates;
  • potassium permanganate;
  • Hydroxycobalamin.

These substances are not recommended to be administered simultaneously. The effect of other compounds on the drug in question has not been studied.

Price

The cost of the medicine varies from 60 to 100 rubles.

Analogs

Substitute drugs with detoxification effect:

  • Amyl nitrite;
  • Unithiol;
  • Deferoxamine;
  • Carboxim, etc.

The first of the drugs is characterized by a vasodilating effect, and at the same time manifests itself as an antidote, intended for use in cyanide poisoning. This medicine has a number of contraindications: intolerance to the active substance (amyl nitrite), nitrates, cerebrovascular accident, hypotension, recent injuries, hyperthyroidism, visual impairment (angle-closure glaucoma), children under 5 years of age, lactation and pregnancy.

Unithiol contains sodium dimercaptopropanesulfonate. It is produced in the form of a solution. This medicine is intended to eliminate the symptoms of intoxication in case of poisoning with highly toxic substances. It is used when the body is damaged by salts of heavy metals, arsenic, cardiac glycosides, and strong alcoholic intoxication. The drug is not prescribed during pregnancy, lactation, hypotension, children under 18 years of age, with liver dysfunction, hypersensitivity to the active ingredient.

Deferoxamine is recommended for use in a pathological condition opposite to iron deficiency anemia. So, this medicine is prescribed if the content of hemosiderin (an iron-containing pigment) increases in the tissues. The drug also helps to normalize the level of aluminum in the body. It is not used when carrying a child, anuria, as well as a developing hypersensitivity reaction. If signs of the described pathological conditions are found, it is recommended to stop lactation.

Carboxime is available in the form of a solution for intramuscular administration. The drug contains the active substance of the same name. It belongs to the group of cholinesterase reactivators. Indications for use: damage by organophosphorus compounds, the emergence of the need to increase the activity of cholinesterase.

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An analogue of Sodium thiosulfate 30% is the drug Carboxim.

This drug is approved for use against the background of antidotes in case of damage to the body with organophosphorus compounds. In this case, the following agents are considered: Athens, Atropine, P-10 M. It is recommended to inject Carboxime 1-2 hours after the injection of the antidote.

Reviews

Natalia, 39 years old, Moscow

Some time ago I used the drug as an auxiliary measure for losing weight. My daily routine in those days: physical activity 6 times a week for 1 hour, proper nutrition, plus I took a dose of this remedy every day. Its advantage lies in the rapid cleansing of the body of toxins, toxins, pathogenic microflora, parasites. After a course of treatment with this remedy, a feeling of lightness appeared.

Galina, 35 years old, Yaroslavl

An excellent medicine: effective, inexpensive, acting quickly, even with severe poisoning. Always in the medicine cabinet. I tried to take it to cleanse the body, in order to lose weight. I did not see the result. Maybe there are some tricks, but after a course of treatment, which lasted 10 days, the weight remained in place.

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