Analysis For Opisthorchiasis: How To Donate Blood, Decoding

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Analysis For Opisthorchiasis: How To Donate Blood, Decoding
Analysis For Opisthorchiasis: How To Donate Blood, Decoding
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Opisthorchiasis is caused by a parasite belonging to the species of flatworms. Such pathogens are called trematodes. This is a rather dangerous disease, the causative agent of opisthorchiasis after scientific research has been identified in the group of carcinogens that cause malignant oncological diseases. Analysis for opisthorchiasis allows you to identify the pathogen in the human body and take appropriate measures.

Content

  • 1 Types of diagnosis of opisthorchiasis
  • 2 Assessment of the result
  • 3 Features of the diagnosis of opisthorchiasis
  • 4 How to prepare for the analysis
  • 5 What happens after the research

A specialist can send for tests for opisthorchiasis with the following patient complaints:

  • Frequent nausea.
  • Regular pain in the epigastric region, heaviness.
  • Heartburn.
  • Frequent pain and discomfort in the right hypochondrium.
  • Fatigue and weakness.
  • The temperature rises to 37.5-38 degrees.
  • Allergic skin rashes in the form of small blisters, itching at the site of the rash.
  • Significant enlargement of the liver.

An infectious disease doctor may be especially alarmed by the fact that the patient has recently consumed river fish, because it is she who is the intermediate host of the causative agent of opisthorchiasis.

Types of diagnostics of opisthorchiasis

Instrumental research methods:

  • Duodenal intubation - a study of bile for the presence of trematode larvae.
  • Ultrasound examination of the abdominal organs.

These two methods are informative in case of extensive infection of the body with trematodes or with high activity of this helminth.

Laboratory research methods:

Blood test for opisthorchiasis

This type of research is a fairly accurate diagnosis of opisthorchiasis. The analysis does not show the presence of fluke eggs, but reveals antibodies. There are two main methods by which blood is most often donated for antibodies in opisthorchiasis.

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  • RNGA (accuracy up to 84%);
  • REMA (accuracy up to 92%).

Analysis of feces for opisthorchiasis

It is possible to diagnose opisthorchiasis by analyzing feces only in the chronic form of the disease, when the eggs of the trematodes come out with the feces and are visible during examination.

This laboratory study usually requires multiple repetitions, at least 4 times, with an interval of 5-7 days.

Result evaluation

It often happens that the results of several analyzes and studies carried out are contradictory, and decoding at the same time requires care and time.

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For example, the enzyme immunoassay showed the presence of the pathogen in the body, and the analysis of feces and duodenal intubation did not reveal the larvae of trematodes. In this case, there are several assumptions:

  • Error due to negligence of the laboratory assistant.
  • The initial stage of the disease, when the parasite has not yet begun to multiply in the organ.
  • Opisthorchiasis has already been cured.

Features of the diagnosis of opisthorchiasis

The most correct approach to the study of the body for opisthorchiasis is the direction to duodenal intubation, and then to the analysis of feces, carried out three times

More often, trematodes are localized in a portion of bile taken during probing. But it must be remembered that the parasite larvae are not in all portions, therefore, duodenal intubation often gives an incorrect result.

How to prepare for analysis

How to get tested, and what should you do before that? Analysis for opisthorchiasis does not require specific preparation.

  • All types of blood tests are taken on an empty stomach in the morning. Venous blood sampling is performed.
  • It is advisable to take the feces as soon as possible after a bowel movement. If this is not possible, then the material can be stored in the refrigerator, but no more than 8 hours.
  • Before duodenal intubation, it is necessary to completely exclude food consumption 20 hours before the start of the study. And three days before probing, you cannot eat foods that cause the formation of an excessive amount of gases in the intestines: cabbage, flour products, sweets, legumes, black bread, soda, etc. If flatulence is still there, then the specialist prescribes enterosorbents - Smecta, Polysorb, Fosfalugel, etc. It happens that the doctor considers it necessary to prescribe antispasmodic and choleretic drugs before probing. This is done so that the eggs of the parasites are thrown out along with the bile - so they are easier to detect with the first duodenal intubation.
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  • Before ultrasound examination of the abdominal cavity, it is also necessary to exclude gas-forming products from the diet. The diet must be adhered to for 3-4 days before the ultrasound, and the study itself must be attended on an empty stomach. If these requirements are not met, the informative value of such a study will be in doubt.
  • Before all types of laboratory and instrumental studies, alcohol and smoking must be completely excluded.

What Happens After Research

If, after all the studies carried out, the diagnosis is nevertheless confirmed, do not panic. The solution to this problem must be completely and completely entrusted to an infectious disease doctor, and in no case self-medicate.

Opisthorchiasis, diagnosed with positive results, needs the following treatment:

  • Symptomatic therapy - antispasmodics (No-shpa, Papaverine) to relieve pain.
  • Antihistamines - Suprastin, Tavegil
  • Enterosorbents - to remove toxins from the body (activated carbon, Smecta)
  • Hepatoprotectors - to protect the liver from the effects of parasites (Urolesan, Silymarin).

This is only one of the stages of treatment, all conservative therapy depends on the severity of the disease and the degree of damage to one or another organ by parasites.

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