Table of contents:
- Mebendazole worm killer
- Release forms
- Indications for use
- Mechanism of action
- Mode of application
- Contraindications and side effects
- special instructions
Video: MEBENDAZOL - Instructions For Use, Price, Reviews And Analogues
Mebendazole worm killer
- 1 Forms of release
- 2 Indications for use
- 3 Mechanism of action
- 4 Method of application
- 5 Contraindications and side effects
- 6 Overdose
- 7 Special instructions
- 8 Reviews
Mebendazole is a synthetic drug. It has a broad anthelmintic effect. The therapeutic effect consists in disrupting the production of glucose, which is necessary for the metabolic processes of worms. Because of this, their vital activity is disrupted, which leads to their inevitable death. Over time, parasites are completely eliminated from the body naturally. The drug is not absorbed by the intestinal walls, which is why it is unevenly distributed in the tissues of the body. The greatest concentration is accumulated in the human liver, adipose tissue and larvae of worms.
Mebendazole is a common worm treatment that is widely used by doctors. It exists in three dosage forms:
- Tablets - 10 mg of active ingredient;
- Suspensions - 20 mg of active ingredient;
- Syrup - 100 mg of active ingredient.
It is best for the attending physician to choose one or another dosage form. He will determine which type of drug is best for you. Do not take Mebendazole as self-medication.
Indications for use
Mebendazole has a wide spectrum of action. It is used to treat helminthic invasion. The drug has extremely positive reviews, many patients have long fallen in love with this drug. Usually, Mebendazole is prescribed to eliminate the following types of parasites:
- Pinworms - they cause enterobiasis;
- Vlasoglava - they cause trichocephalosis;
- Ascaris - they cause ascariasis;
- Intestinal acne - it causes strongyloidosis;
- Hookworm - it causes hookworm;
- Bovine tapeworm - it causes teniidosis;
- Echinococcus larvae - they cause trichinosis;
- Mixed helminths.
Mebendazole can be used to combat several types of pathogenic microorganisms. The drug shows the greatest efficiency in the fight against enterobiasis and trichocephalosis. Be sure to consult your doctor before use.
Mechanism of action
The mechanism of action of the drug
The essence of the therapeutic effect of Mebendazole is based on two main effects. First of all, the active substance disrupts the work of energy metabolism in helminths, which is why adenosine triphosphate cannot be produced in them. Also, worms cannot accumulate and use glucose, which they need for normal life. Because of this, they gradually weaken, after which they undoubtedly die off and are completely eliminated from the body.
Also, the components of Mebendazole interfere with the production of proteins that build the cellular skeleton of parasitic cells. Because of this, their body also stops producing tubulin, without which their structure undergoes major changes. Over time, this also leads to the massive death of helminths. Studies have shown that the drug is poorly absorbed by the gastrointestinal tract, it enters the bloodstream and then spreads throughout the body.
The components accumulate unevenly in tissues, but quickly penetrate into the organisms of helminths. This stops their growth, prevents reproduction. After work, half-life products are released into the bloodstream, which then enter the liver and are excreted by the genitourinary system. Dead parasites are excreted from the body naturally unchanged. The medicine is absolutely safe when used correctly.
Mode of application
It is strictly forbidden to take Mebendazole as self-medication. Such therapy can easily cause serious complications. Remember, only your doctor can prescribe this medication for you. The specialist must take into account the individual characteristics of the body, the presence of any chronic diseases. It is necessary to take Mebendazole in any dosage form after meals with plenty of water. The method of application is as follows:
- For the treatment of enterobiasis - 1 tablet once, after 2-4 weeks, repeat the application;
- For the treatment of trichinosis - 2-4 tablets per day for 3 days (after a week break, take 4-5 tablets per day for 5 days);
- For the treatment of echinococcosis - the first three days - 5 tablets twice a day, the next 3 days - 5 tablets three times a day, on the last day - 25 mg of the drug per 1 kg of human weight;
- For the treatment of other helminths - 1 tablet per day for 3 days.
It is not recommended to use Mebendazole as a prophylaxis. The medicine is powerful enough, it must be used strictly in the presence of parasites. Also, before prescribing, it is necessary to determine the type of pathogen in order to understand exactly whether the therapy will be effective or not.
If you do not use Mebendazole according to the instructions, then there is a high risk of side effects. Children can only take medicine when they reach 2 years of age. If the patient is over 10 years old, then the adult dose is applied to him.
Contraindications and side effects
In order to prevent any dangerous consequences from occurring, it is very important not to use Mebendazole if there are contraindications. It is strictly forbidden to use the drug in the following cases:
- Pregnant and lactating women;
- With renal and hepatic insufficiency;
- With high sensitivity to components;
- Children under 2 years old;
- With diseases of the nervous system.
If you do not follow the restrictions or take the medication incorrectly, you run the risk of facing serious side effects. Most often there are:
- Dizziness and headache;
- Nausea and vomiting;
- Abdominal pain, stomach cramps;
- Anemia and leukopenia;
- Allergic reaction;
- Hair loss;
- Increased blood pressure.
It is very important to observe the exact dosage of the drug. Otherwise, the person may overdose. Its signs can be recognized by the following symptoms:
- Stomach ache;
- Decrease in blood pressure and light-headedness.
Keep in mind that with prolonged use of Mebendazole, a person experiences serious abnormalities in the liver: neutropenia and hepatitis. To prevent such consequences from occurring, it is very important to visit your doctor regularly. Overdose requires compulsory treatment: it is necessary to rinse the stomach, take activated charcoal and do an enema. No specific medications are required.
Control blood sampling
If you are going to use Mebendazole for a long time, you should regularly visit your doctor and get tested. It is very important to monitor the condition of all internal organs, especially the kidneys and liver, as they are most affected. It is strictly forbidden to consume alcohol during therapy with this medicine. The fact is that when the active substances are mixed with alcohol, a mixture is obtained that has an extremely negative effect on the condition of the liver.
It is strictly forbidden to use laxatives during treatment with a worm with Mebendazole. Be sure to undergo a diagnostic fecal examination at the end of treatment. It is also necessary to take a smear of the anus, which will show whether the larvae remain in the body or not. You need to take the analysis after 1 week from the date of completion of treatment.
Mebendazole can be used to treat helminthiasis in children. The manufacturer allows taking this medication in a child who is over 2 years old. If children have not yet reached the age of 10, then they can take a single dose of 25-50 mg of the drug. If the child is more than 10 years old, then the dose for the treatment of helminths for them is the same as for adults. The World Health Organization recommends that children from 2 to 5 years old drink Mebendazole at least once a year as a prophylaxis.
The manufacturer does not recommend the use of Mebendazole for pregnant and lactating women. The drug is actively distributed throughout the body, can penetrate the placenta and into breast milk. The only exception when the medicine can be taken is when the benefit to the mother is much greater than the possible harm to the child.
Be sure to consult your doctor if you are using any medications other than Mebendazole. For example, cimetidine can increase the concentration of an active substance in the blood. In turn, carbamazepine reduces the activity of the components. It is strictly forbidden to take fat-soluble drugs while taking Mebendazole.