Analysis Of Ureaplasma In Women - The Norm, Deciphering How The Analysis Is Taken

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Analysis Of Ureaplasma In Women - The Norm, Deciphering How The Analysis Is Taken
Analysis Of Ureaplasma In Women - The Norm, Deciphering How The Analysis Is Taken
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Do women need an analysis for ureaplasma

Content

  • 1 Information about ureaplasma
  • 2 How ureaplasma is detected
  • 3 Problems in the interpretation of tests for ureaplasma
  • 4 Information about the danger of ureaplasma
  • 5 Arguments about the relative harmlessness of mycoplasmas
  • 6 Responsibility of choice for the treatment of ureaplasmosis

The analysis for ureaplasma in women has become a matter of controversy in scientific medical circles. Some insist on the insidiousness of the microorganism, the latent threat of delayed ailments and breakdowns, complicated pregnancy, up to miscarriage. At the same time, some make good money, exploiting human fear for their health. Others tend to rely only on experimentally confirmed facts, shifting the responsibility of choice to the patient, and the question of the clinical significance of the infection itself is questioned.

Let's try to cut off commercial myths from medical data, tell about the true danger of ureaplasma, so that a person is aware of what he is facing.

Information about ureaplasma

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Information about ureaplasma

The microorganism belongs to the mycoplasma family - the smallest bacteria that do not have their own cell wall, which makes them less vulnerable to most antibiotics. Mycoplasmas (mollicuts) occupy an intermediate position between viruses and unicellular microbes.

Ureaplasma "sticks" to the cell membrane of the epithelium lining the urogenital area, as well as to spermatozoa, erythrocytes, granulocytes. It is a membrane parasite that feeds on urea, being in symbiosis with a healthy host.

Although this diagnosis is not listed in the International Classification of Diseases, it is considered when, in the presence of inflammation, no more significant pathogenic factors have been identified. Ureaplasma and mycoplasma as a specified pathogen are included in the diagnoses:

  • Cervicitis (code N72.0 + B96.8);
  • Urethritis (code N34.0 + B96.8);
  • Vaginitis (code B07.0 + B96.8).

Given the recent beginning of research on ureaplasma and its pathogenic role, the study of the microorganism continues. Two biologically significant variants of ureaplasma were found: urealyticum and parvum, and the urealyticum biovar is less common and more dangerous. A person can be a carrier of one of them, or both at the same time. Mycoplasmas are considered to be conditionally pathogenic flora, capable of causing harm only to people with a deficiency of immunity.

Today, a consensus has been adopted: the very fact of detecting ureaplasma parvum and urealiticum in a woman in the analyzes is the norm, if the numbers are insignificant, there are no complaints. Treatment for a single reason - a positive test, is not performed.

If the disease is present, and laboratory data do not show other pathogens, except for an increased level of ureaplasma, a diagnosis of "ureaplasmosis" is made. They are treated with broad-spectrum antibiotics (tetracycline, erythromycin, doxycycline, ofloxacin, azithromycin), based on the sensitivity test results.

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Tetracycline

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Erythromycin

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Doxycycline

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Ofloxacin

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Azithromycin

Important! A different picture before the planned pregnancy or during its course. A woman whose analyzes have shown the presence of ureaplasma has the right to know that hormonal changes can reduce local immune defenses. This provokes the multiplication of pathogens suspected of causing miscarriage, premature fetus, pneumonia of the newborn.

How is ureaplasma detected?

Today, accurate laboratory methods, in combination, make it possible to identify with high reliability both the ureaplasma itself and the antibodies to it produced by the immune system. Any single method will show a contradictory picture, therefore, a set of analyzes is prescribed. Responsible doctors simultaneously take tests for ureaplasma in women, which include:

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  • Serological examination of blood serum (IgG, IgA);
  • Microbiological analysis (culture with antibiotic sensitivity control);
  • PCR (polymesar reaction) technique for detecting the DNA of the pathogen.

For serology, venous blood is taken, for microbiology and PCR - biological fluids (urine, in men also prostate secretion, sperm), epithelial cells of the genitourinary tract.

Note! Before taking the analysis, a woman needs to know that the menstrual cycle affects the hormonal background and the balance of microflora. In order not to get a false positive answer, you should, on the recommendation of a doctor, choose the optimal time for sampling.

It is desirable to repeat the examination after 2 weeks in order to trace the dynamics of the growth of microorganisms. After antimicrobial therapy, it is important to control the cure of the disease - if the result is negative, ureaplasma and other bacteria are excluded as a pathogenic factor.

Problems in the interpretation of tests for ureaplasma

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Problems in the interpretation of tests for ureaplasma

Practicing doctors are of the opinion that a contamination rate of up to 104 CFU per 1 ml is acceptable, above it is considered dangerous and should be treated. In the scientific literature, there are no convincing data on such figures, there are only assumptions.

The problem of interpreting tests for ureaplasma remains unresolved - each doctor takes his own responsibility, analyzing the clinical picture of each individual patient, makes an informed decision about the advisability of combating the microbe.

An honest doctor must inform the patient of the risks discovered by medical research, but at the same time give up trying to intimidate and cash in on his gullibility. Some sin with the commercial temptation, attributing mythical horrors to mycoplasmas, thereby persuading the patient to expensive, often useless, treatment.

Information about the danger of ureaplasma

What is mycoplasma really to blame, what are they suspected of, based on research results?

Separate data on the effect of urealyticum contamination with ureaplasma on women's health concern:

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  • Inflammation of the urogenital tract, uterus, genital appendages;
  • Pathological course of pregnancy;
  • Miscarriages;
  • Ectopic pregnancy;
  • Formations in the pipes of adhesions;
  • Low birth weight;
  • Pneumonia of the newborn;
  • Infertility.

Male sex is at risk of urethritis, impaired spermatogenesis (sedentary and immobile spermatozoa), prostatitis, damage to the organs of movement.

Arguments about the relative harmlessness of mycoplasmas

Examining healthy women without complaints and clinical signs of the disease, ureaplasma parvum is found in analyzes in 80 - 90% of representatives of reproductive age, urealyticum in 30%. At the same time, women normally carry fetuses and give birth to healthy babies.

Analyzing individual data on the dangers of mycoplasmas, it is difficult to trace the cause-and-effect relationship. Indeed, in patients with these ailments, an increased dissemination of the urealyticum was revealed, but its role as a triggering mechanism is not yet clear.

Note! It is fair to talk about the risks for persons with impaired immune defense function, microflora imbalance, and immunodeficiency states. Such people need to be sure to treat ureaplasmosis.

With regard to the feasibility of treating asymptomatic ureplasma, preventive therapy is not practiced in the world. Treatment is prescribed solely according to obvious indicators - the presence of complaints, obvious symptoms, positive laboratory results.

Important! In the case of diagnosing urethritis, cervicitis, vaginitis, therapy is required, even when the pathogen has not been identified.

During pregnancy, if a genital infection is detected, included in the list of TORCH infections (dangerous to the fetus), then when the pathogen is destroyed with antibiotics, ureaplasma will also suffer, since it is sensitive to the prescribed drugs.

Mycoplasmas themselves are not currently included in the list of TORCH infections, therefore, they should not be treated only when the analysis is positive, during gestation, especially if the pregnancy proceeds without problems from the genitals. The negative effect of therapy may outweigh the therapeutic outcome. There is evidence that antibiotics during pregnancy do not protect against premature birth.

Responsibility of choice for the treatment of ureaplasmosis

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Responsibility of choice for the treatment of ureaplasmosis

The problem of medical ethics especially concerns ureaplasmosis. Lacking unequivocal conclusions of medical science, a decent doctor must take a responsible attitude towards the choice in favor of treatment or refusal of it, weigh the pros and cons.

It is important to convey truthful information to the patient, to tell about potential threats, if he has the prerequisites. Send for tests when there are good reasons. Prescribe justified treatment.

An informed person will make an independent decision whether to harass ureaplasma or coexist with it further, like other millions of earthlings.

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