ALBENDAZOLE - Instructions For Use, Price, Reviews And Analogues

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ALBENDAZOLE - Instructions For Use, Price, Reviews And Analogues
ALBENDAZOLE - Instructions For Use, Price, Reviews And Analogues

Video: ALBENDAZOLE - Instructions For Use, Price, Reviews And Analogues

Video: ALBENDAZOLE - Instructions For Use, Price, Reviews And Analogues
Video: How To Take Albendazole | Albendazole Syrup Kab aur Kaise Le | Uses Dose Side Effects Price | Hindi 2023, December

Proven anthelmintic agent Albendazole


  • 1 Albendazole - composition, form of release
  • 2 Properties
  • 3 Indications for use
  • 4 Contraindications
  • 5 Adverse reactions
  • 6 Albendazole - instructions for use
  • 7 Albendazole for prophylaxis
  • 8 Special instructions
  • 9 Interaction
  • 10 Albendazole: analogues

    • 10.1 Albendazole or Nemozole: which is better?
    • 10.2 Albendazole or Pirantel which is better?
    • 10.3 Albendazole or Mebendazole: Which is Better?
  • 11 Albendazole and alcohol
  • 12 Influence on the ability to drive vehicles and use machinery
  • 13 Pregnancy and Albendazole
  • 14 Reviews

Infection with helminths is a common disease. There are many drugs to combat it, Albendazole is one of them. This drug has existed on the pharmaceutical market for a very long time, about forty years. And all these years it has been proving its effectiveness and efficiency, showing excellent results in the fight against parasites. Its manufacturer is an Indian company.

Albendazole - composition, release form


Albendazole - composition, release form

The main component of albendazole is albendazole, which served as the basis for many anthelmintic drugs. It exists in several forms, which allows you to easily build a treatment regimen with this drug for both children and adults. For babies, Albendazole is available in suspension form. Its concentration is different. 2.5 mg of the active ingredient and 10 mg per 100 ml of the drug.

In addition to albendazole, the suspension contains auxiliary substances that help its better absorption. Take the syrup orally before meals. Before use, be sure to shake, as the composition includes water-insoluble suspensions.


Albendazole is a broad-spectrum anthelmintic drug. Its properties of action on parasites determines the main component.


Albindazole penetrates into the intestinal tissue of helminths

Albindazole performs its function due to its ability to penetrate into the intestinal tissue of helminths, where it binds to the proteins tubulins, preventing further recreation of the formation of microtubules, which are necessary for the migration of particles in the body. As a result of this work, glucose and fumarate reductose become nontransportable. Why the helminths become unable to lay eggs, the larvae stop forming.

Due to the suppression of this vital function, helminths lose their ability to move and further reproduce. Albendazol actively fights only against larvae and adults of parasites, eggs are not susceptible to its influence. Once inside, albendazole is absorbed. Its absorption in the body is only 5 percent. Fatty foods enhance the absorption process, which can lead to overdose or cause adverse reactions.

Albendazole goes through a dual metabolic process. The first stage takes place in the liver, where the active substance is transformed into albendazole sulfoxide. After 2, maximum 5 hours in the body, the maximum concentration of this substance is reached. It actively enters into a bond with plasma proteins and is well distributed, quickly penetrating into many fluids and organs.

During the second stage of metabolism, which takes place there in the liver, albendazole sulfone is formed. Its half-life is quite long, 8-12 hours. A small amount is excreted from the body through urine. However, a larger volume enters the intestine, from where it is excreted along with waste products.

It should be borne in mind that in the case of existing liver diseases, the bioavailability of the drug is doubled. The half-life is also doubled. This can cause serious adverse reactions. Therefore, in the presence of liver disease, the drug should be taken with extreme caution.

Indications for use

The drug is prescribed for the following pathologies:

  • Neurocysticercosis. Helminthic infection of the nervous system caused by the larvae of the pork tapeworm.
  • Echinococcus of the abdominal organs. This disease is chronic, it provokes echinococcus, most often settles in the liver, lungs, causing damage to these organs and provoking their dysfunction.
  • Arachnoid, racemose, internal cysts. Diseases provoked by the larvae of the pork tapeworm, penetrating the internal organs.
  • Ascariasis. Helminthic invasion, the causative agent of this disease is roundworms parasitizing in the small intestine. This disease is called dirty hand disease. Most often it occurs in children of preschool and primary school age.
  • Enterobiasis. Perhaps the most common helminthiasis. It is caused by a pinworm - a small white worm. The length of the female is only 10 mm, the male is even less - 5 mm.
  • Ankylostamidosis. Infestation caused by small worms - hookworms.
  • Opisthorchiasis. A chronic disease caused by parasitic flatworms that inhabit human organs. His provocateur is a fluke.

  • Trichinosis. Helminthiasis, which is characterized by fever, rashes, swelling of the face and other manifestations. Affects internal organs. Its causative agent is Trichinella.
  • Toxacorosis. A widespread parasitic disease caused by toxocara.
  • Capillarosis. A helminthic invasion caused by one of the capillary worms, depending on its type, can affect the intestines, liver or lungs.
  • Microspiridosis. Usually appears in the body with weakened immunity. It is caused by microsporidia.
  • Gnatostomosis. It is characterized by knotty formations under the skin no larger than a pea. Affects skin, central nervous system, eyes, lungs.

Albendazole is prescribed after surgery to reduce cysts. Effective in the treatment of mixed invasions.


Despite the fact that the drug is well known and is often prescribed for the treatment of various kinds of invasions, it should be used with caution and not deviated from the scheme outlined by the doctor.

  • You can not use this remedy in the presence of intolerance to the main or any auxiliary component;
  • Pregnancy and breastfeeding are also a strong contraindication;
  • In children under one year of age, the drug is also undesirable;
  • In the presence of chronic gastrointestinal diseases or cardiac or vascular disorders in elderly patients.

The drug is not contraindicated, but it must be used with extreme caution in the following diagnoses and conditions.

  • Depression of brain function;
  • Cirrhosis of the liver;
  • Liver failure;
  • Cysticercosis of the eyes.

Adverse reactions

As a result of taking the drug, there is a likelihood of developing adverse reactions:

  • There is a possibility of gastrointestinal disorders - vomiting, nausea, pain in the stomach, bloating and even diarrhea may appear;
  • Dizziness, migraines are not excluded;
  • Allergic reaction in the form of skin redness, itching;
  • It is extremely rare, but there is still a chance of hair loss.

To reduce the risk of adverse reactions, you should strictly follow the scheme prescribed by your doctor. All adverse reactions are reversible. To stop them, you should immediately stop taking the drug and seek the advice of a doctor.

Albendazole - instructions for use

The dosage in each individual case is assigned individually. It depends on the severity of the course of the disease, weight and age of the patient. The portability of the components also matters.

For children, Albendazole is most often prescribed as a suspension. You can give it only at the age of one year. The drug should be taken once with meals. We must not forget that fatty foods increase the absorption of the drug, which can lead to overdose.

  • With enterobiasis, ankylostomiasis and ascariasis, children under 2 years of age should be given 200 mg of the active ingredient or 10 ml of suspension. Children over 2 years old are given 400 mg of the active ingredient or 20 ml of the drug.
  • Trichanallosis and toxocariasis. With these diseases, Albendazole is given only from 2 years old. Prescribed according to the formula: 10 mg of the active ingredient per kg of the child's weight. It should be taken for 5-10 days.
  • Echinococcosis. The daily rate should not exceed 15 mg of active substance per kg of body weight. Divide the resulting volume into two steps. Take a month.
  • Giardiasis. Take 400 mg of the active ingredient daily for five days.
  • Opisthorchiasis. The same 400 mg of the active substance, but the duration of administration is three days.

The pills have a completely different treatment regimen. They are most often prescribed to patients over 18 years of age. Each individual disease has its own treatment regimen.

  • With enterobiasis, ankylostomiasis and ascariasis, one should take a tablet 400 mg once a day. The course is two weeks. After two weeks, the course should be repeated.
  • Echinococcosis. Patients weighing less than 60 kg should take 15 mg for each kg of their weight. Take the resulting volume once a day.
  • If you weigh over 60 kg, 400 mg twice a day. The general course is four weeks. Then you need to interrupt for two weeks and repeat the treatment again from the very beginning.
  • Filariasis. 400 mg twice a day, regardless of weight. Take at least 10 days.
  • Toxocariasis. Take a 400 mg tablet twice a day. The general course is 5 days.

  • Strongyloidosis. Two tablets a day, should be taken throughout the week.
  • Trichinosis. Take one 400 mg tablet per day. Reception lasts three days. In the case of several types of flukes or the condition is too neglected, 10 mg of the active ingredient should be taken according to the formula for each kg of patient weight. The course is equal to a week.
  • Cysticercosis. Take a tablet twice a day for 8 days.
  • Giardiasis. Half a tablet twice a day with breakfast and dinner. You need to take a week.

Here are just some of the possible schemes. A more detailed and correct dosage and frequency of administration can only be calculated by the attending physician. In no case should you change the dosage and time of taking the drug on your own.

This drug is widely used not only in the treatment of helminthiasis in humans, but also in animals. There are also dosages for them. It is easiest to use the drug in the form of a suspension with a concentration of 2.5% for small animals and 10% for cattle.

  • Cats and dogs are prescribed 0.3 ml;
  • Small ruminants are prescribed 0.7 ml;
  • Large horned - 1 ml.

It is prescribed for the treatment of nematodyrosis, bunostomosis, cooperiosis, moniesiasis, heterocytosis and others. Typically, the course of treatment is a couple of days. The drug is mixed into food in the morning. It should not be given in hot food, nor should it be given to pregnant animals. Albendazole is often prescribed as a prophylactic agent.

Albendazole for prophylaxis

Parasitic diseases are very harmful to any organism. And many, trying to prevent the serious consequences of these diseases, take anthelmintic drugs as a prophylaxis. However, not every medicine is suitable for such purposes.

Due to the fact that Albendazole is a fairly strong medication that has a toxic effect, it should not be taken as a prophylactic drug without a doctor's recommendation. For this purpose, it is better to choose less toxic substances. For the correct appointment of a prophylactic agent, you should consult a doctor, only he will be able to choose the most adequate remedy in each individual case with the least list of adverse reactions.

special instructions

Before starting treatment, no additional procedures for cleaning the body should be carried out. The drug course also does not provide for special diets.


In the first weeks of the medication course, a blood test should be monitored. The level of leukocytes should be monitored, which can drop sharply as a result of ingestion. It also requires monitoring of aminotransferases, which, on the contrary, may increase. In case of deviations from the norm, you should immediately stop taking the drug until the tests completely return to normal.

In case of liver dysfunction, constant monitoring of its work is needed. This analysis should be done in the middle of each course. In case of deviations from the norm, the drug should also be discontinued until the patient's condition is completely normalized.

To have a complete picture of the patient's condition, it is necessary to conduct an examination of the body before starting the medication course. To minimize the likelihood of re-infection of the body with helminths, you should thoroughly clean the apartment before taking the drug. Clean floors, children's toys. On the day of the start of treatment, you should change the bedding, before thoroughly treating it with a hot iron. In the evening and in the morning take a shower and change your underwear.

During treatment, bed linen should be thoroughly treated with a hot iron, and underwear should be changed frequently. Carefully monitor personal hygiene. Wash hands with soap and water for at least three minutes. Only after such a time, most microbes and bacteria die on the hands. Cut your nails short and avoid scratching the anus.

In the case of treatment of enterobiasis and ascariasis, preventive treatment should be carried out in all people who are in close contact with the patient.

It should be remembered that these diseases can occur in a latent form, and it can only be recognized after passing the tests. A prophylactic agent should be prescribed by a doctor, since Albendazole has a lot of contraindications. The drug is highly toxic. For prevention, it is better to choose something else.


Cimetidine, Dexamethasone and Praziquantel can lead to an overdose and increase adverse reactions from taking Albendazole, since as a result of such a tandem, the content of the latter in the blood increases significantly.







Albendazole: analogues

It has quite a lot of analogues both in terms of the active ingredient and the effect on the body. This drug is not the cheapest of its analogues, it costs about 170 rubles. It is impossible to independently change a prescribed drug to its analogue, even a structural one. Even with the same component as the main one, medicines can have completely different effects on the body.

  • Zentel. A fairly cheap structural analogue of Albendazole, its price fluctuates around 70 rubles. Used in the treatment of intestinal invasions. It can be prescribed from the age of three. Also available in suspension and tablets.
  • Aldazole. Also a structural analogue of Albendazole. Available only in pill form, which makes it difficult to use in children. It also affects helminths of various groups. There are contraindications, it is quite toxic. At a cost lower than its main competitor - about 800 rubles.
  • Vermox. Perhaps the most common of the analogues. It is based on mebendazole. It is produced in the form of tablets and suspensions, which allows you to measure out the dosage even in early childhood. Can be used from two years of age. The list of contraindications is not as wide as that of Albendazole, while according to the list of indications it is not inferior to its brother. Its cost does not exceed one hundred rubles.







Albendazole or Nemozole: which is better?


The second is a fairly profitable replacement for the first. Also available in suspension and tablet form. The effect on the body is identical. At cost they are equal. Due to the fact that both are based on albendazole, they have an identical effect on the body. The list of indications and contraindications is the same.

Albendazole or Pirantel which is better?



Pirantel, unlike Albendazole, is a less toxic drug, therefore it is very often recommended just as a preventive measure. However, unlike its counterpart, it only affects round helminths, which significantly narrows its range of application. Available in syrup and chewable tablets. The cost of the latter in the pharmacy is low, only 20 rubles per pack.

Albendazole or Mebendazole: which is better?



Both drugs are anthelmintic. They differ in the active ingredient, the second contains mebendazole. The latter is very good at fighting adult parasites, as a rule, this drug is prescribed at the beginning of treatment. It is very good for combined helminthic invasions. But Albendazole also works against the larvae of parasites, which significantly expands its drug capabilities.

Albendazole and alcohol

It is very poorly tolerated against the background of alcohol, therefore, doctors strongly recommend not to take alcohol during treatment:

  • Development of liver failure;
  • The appearance of cutting pain in the right hypochondrium;
  • Yellowing of the skin;
  • Vomiting;
  • Dizziness.

These are just some of the symptoms likely to occur when spirits and Albendazole are combined. If treatment is not carried out on time, the onset of severe complications is likely, up to a lethal outcome.

Influence on the ability to drive vehicles and control mechanisms

During treatment with Albendazole, it is better to avoid driving, as there is a high likelihood of dizziness and other adverse reactions.

Pregnancy and Albendazole


Albendazole should not be taken during pregnancy, it is worth clarifying that in this state, treatment against helminths is not carried out at all. Since all drugs in this direction penetrate the placenta and can cause abnormalities in the development of the fetus. Before prescribing an anthelmintic for women of childbearing age, make sure she is not in position.

Albendazole should not be taken during breastfeeding either. If treatment is necessary, you should refuse to feed the baby with milk during the course of the therapeutic course.