PIRANTEL - Instructions For Use, Price, Reviews And Analogues

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PIRANTEL - Instructions For Use, Price, Reviews And Analogues
PIRANTEL - Instructions For Use, Price, Reviews And Analogues

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Modern antihelminthic agent Pirantel

Content

  • 1 Composition and form of release
  • 2 Properties
  • 3 Purpose
  • 4 Nemozol - instructions for use
  • 5 Overdose
  • 6 Contraindications
  • 7 Side effects
  • 8 Interaction
  • 9 Analogs

    • 9.1 Biltricide
    • 9.2 Piperazine
    • 9.3 Pyrvinium
    • 9.4 Telmox 100
    • 9.5 Mendalin
    • 9.6 Nemocide
    • 9.7 Decaris or Pirantel: which is better?
    • 9.8 Pirantel or Helmintox: which is better?
  • 10 Special instructions

    • 10.1 Pirantel during pregnancy and lactation
    • 10.2 Pirantel and alcohol
    • 10.3 Influence on the ability to drive vehicles and use machinery
  • 11 Reviews

Pirantel is a modern drug used as an antihelminthic agent. Practically has no contraindications, even small children are prescribed in the form of syrup. However, it should be remembered that no medicine should be taken without permission. You should always consult with a therapist. A person may develop diseases in which the drug gives a serious complication.

Composition and form of release

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Release forms

Available in the form of tablets and suspensions. Includes pyrantel as the main ingredient. The tablets are 250 mg. In liquid form, there is also 250 mg of active ingredient per 5 ml.

Properties

Anthelmintic agent. As a result of taking the drug in parasites susceptible to the main component, neuromuscular paralysis occurs. As a result, they become immobilized and lose their ability to stay in the human body. Together with excrement, parasites are excreted from the intestines. Both very young and mature individuals are equally susceptible to pyrantel. Absolutely useless against larvae.

Effectively works against pinworms, hookworms, and trichocephalosis and ascariasis are susceptible to its effects. It is poorly absorbed by the body. The maximum blood content is reached after 1-3 hours. In a small volume, it is metabolized in the liver. Almost 93 percent is excreted through the intestines unchanged, the remaining 7 - by the kidneys.

Appointment

Diseases against which Pirantel works effectively are ascariasis, ankylostomiasis, noncatorosis and enterobiasis.

Nemozol - instructions for use

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The drug in tablets can be taken from the age of six. For children under this age and body weight up to 12 kg, it is better to give the drug in the form of a syrup.

Before taking the medicine, the bottle must be shaken thoroughly so that the active ingredient is evenly distributed in the liquid. Since the calculation of the dosage in each specific case occurs individually, you should know that 50 mg of the main component goes to 1 ml of syrup. Assuming that the supplied 2.5 ml measuring spoon contains 125 mg of pyrantel.

There are no special indications for taking the drug. You can take it at any convenient time of the day. No special diet or prior intake of laxative medications and procedures is required.

The course of treatment is short-term - the drug is taken in the required amount once. In the treatment of enterobiasis and ascariasis, the drug is calculated from the formula 12.5 mg / kg of body weight.

So when treating children under the age of 6 years, for every 10 kg of body weight, you need to give 1 measuring spoon. Pills at this age are not prescribed.

For children from 6 years to 14, the calculation is the same - 1 measuring spoon per 10 kg of weight. You can give tablets instead of syrup. The calculation is as follows. 1/2 tablet of 250 mg per 10 kg of body weight. That is, a child with a weight of 25 kg should be given two and a half measuring spoons or a tablet plus a quarter to drink.

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Adult patients up to 75 kg need to take 6 measuring spoons or 3 tablets of 250 mg. With a body weight over this weight, you should drink 8 measuring spoons or 4 tablets.

To consolidate the result and prevent re-infection, it is recommended to repeat the procedure after three weeks.

In case of hookworm disease or other combinations of diseases, the drug should be taken for three days at the rate of 10 mg per kg of patient weight. The resulting volume is taken at a time with water. You can carry out the treatment in two days, then the calculation of the volume of the drug is carried out according to the formula per day or you can drink the drug for two days at 20 mg.

In case of a disease only with ascariasis, the drug should be taken at the rate of 5 mg of active substance per kg of body weight, a single dose.

In endemic zones, with ankylostomiasis disease or its severe form, treatment should be carried out for three days when calculating the drug according to the formula 25 mg / kg of body weight. Divide the resulting volume into several servings and take during the day. Outside the endemic zone, the dosage is half and the pills are taken once. The tablets must be chewed.

Before treatment, no bowel cleansing procedures are necessary. If you undergo a course of enterobiasis, for the purpose of prevention, the whole family should drink the drug. Two weeks after treatment, research should be carried out to determine the effectiveness of the therapy, in case of negative results, repeat the entire treatment from the beginning.

Overdose

Since the drug is very poorly absorbed, the likelihood of an overdose is unlikely. Even in the case of its manifestation, there are no signs of serious intoxication.

In case of an overdose, consequences such as loss of appetite, nausea with vomiting, diarrhea are possible. Dizziness, migraines, sleep disturbances, overexcitation, weakness are possible. In some cases, a rash may appear on the skin, and the production of a liver enzyme may also increase.

There is no specific antidote against the effects of pyrantel. First of all, you should rinse the stomach by taking as much warm water as possible and pressing on the root of the tongue to induce vomiting. Until the patient's condition returns to normal, it is necessary to monitor the work of the heart and monitor the stability of breathing. If necessary, symptomatic treatment is prescribed.

Contraindications

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  • Increased susceptibility to any component is a reason to refuse taking pyrantel in favor of an analogue;
  • Pirantel should not be taken in combination with Piperazine; for the duration of treatment with the first drug, it is worth temporarily refusing to also choose a more suitable analogue;
  • Do not take Pirantel while treating myasenia;

Side effects

Adverse reactions from taking pyrantel are extremely rare, but still occur. They are short-lived and pass very quickly. The digestive system is mainly affected. Upset stomach, vomiting and diarrhea. Stomach cramps and pain, loss of appetite are likely. Much less often there is a headache and dizziness, weakness, insomnia may appear, sometimes it is overexcitation and a rash, possibly a fever.

Very rarely, the activity of transaminases in the blood may increase. The appearance of auditory hallucinations and confusion in reasoning is extremely rare.

Interaction

The drug should not be administered together with Piperazine and Levamisole. With such a complex, the effectiveness of Pirantel is significantly reduced. These drugs must be drunk sequentially.

Pirantel is able to significantly increase the concentration of Theophylline in the blood. Therefore, these drugs are also not allowed in one complex.

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Levamisole

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Theophylline

Analogs

There are many analogues of Pirantel. Despite the fact that this drug is significantly inexpensive, from 19 rubles per pack, in some cases, for various reasons, you have to choose analogues.

Biltricide

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Biltricide

The drug is based on praziquantel. Has a wider range of effects than Pirantel, works against tapeworms, bovine, Chinese fluke and others. Copes with parasite larvae. It has a number of contraindications, the likelihood of side effects is also high. At the same time, it is quite expensive, 1800 per package.

Piperazine

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Piperazine

He has a narrower range of purposes than Pirantel. It is prescribed only for roundworms and pinworms, it is useless from other helminths. The price is even lower than Pirantel, only 10 rubles.

Pyrvinium

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Pyrvinium

The preparation is based on pyrvinia embonate. It has a fairly narrow spectrum of effects on helminths - only pinworms. There are practically no contraindications. Adverse reactions are minimal.

Telmox 100

Acts on the basis of mebendazole. Effectively works against pinworms, roundworms, hookworms, nekator, intestinal acne, echinococcus and pork tapeworms. Has a number of contraindications and side effects. In pharmacies, this drug is offered for 170 rubles.

Mendalin

Based on carbendacim. It copes well with such helminths as intestinal acne, hookworm, nekator, pinworm, roundworm, whipworm. It also has a number of contraindications and side effects.

Nemocide

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Nemocide

Ascaris, nekator, are used with caution in babies up to six months. Loyal enough and has minor contraindications and side reactions. The cost exceeds Pirantel by almost four times. The pharmacy will ask for 75 rubles for it.

Decaris or Pirantel: which is better?

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Decaris or Pirantel: which is better?

Decaris has a completely different composition, its main component is levamisole. Effectively works against hookworms, ascaris, nekator, intestinal acne, trichostrongylids, whipworms, pinworms and toxoplasma. At the price, Dekaris is three times higher than Pirantel.

Pirantel or Helmintox: which is better?

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Pirantel or Helmintox: which is better?

Helmintex has a slightly narrower range of applications. But at the same time it has a rather serious effect on the liver, therefore, in case of problems with this organ, it is prescribed very carefully. Its price is also an order of magnitude higher than Pirantel - 76 rubles.

special instructions

The drug should be used with extreme caution in children under two years of age. Existing liver disorders can also be the reason for the refusal of this medication. If the patient is undergoing treatment against enterobiasis, all family members should undergo treatment in parallel with him.

To avoid infection with helminths, you need to carefully monitor your personal hygiene: wash your hands with soap, clean clothes well, clean the premises regularly and wash children's toys. All this will allow you to destroy helminth eggs.

Three weeks after completing the course, you need to undergo repeated treatment in order to prevent and prevent a recurrence of the disease.

Pirantel during pregnancy and lactation

This drug is not taken during pregnancy and lactation. Its appointment is possible only if the intended benefit outweighs the likely risk from treatment.

During the period of treatment, it is more advisable to refuse breastfeeding during the course of treatment.

Pirantel and alcohol

There are no direct contraindications to drinking alcohol while undergoing treatment with Pirantel, but doctors strongly recommend abandoning such a duet. Alcohol can provoke adverse drug reactions, increase dizziness and stress on the liver.

Influence on the ability to drive vehicles and control mechanisms

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Pirantel and car driving

During Pirantel's treatment, driving and other activities that require attention, quick response and concentration are not prohibited. In some cases, if a side effect such as dizziness occurs when using this drug, these activities and driving should be avoided.

Reviews

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