The Best And Most Effective Antibiotics For Ureaplasma

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The Best And Most Effective Antibiotics For Ureaplasma
The Best And Most Effective Antibiotics For Ureaplasma

Video: The Best And Most Effective Antibiotics For Ureaplasma

Video: The Best And Most Effective Antibiotics For Ureaplasma
Video: Ureaplasma urealyticum Infection - 6 Month Follow Up 2023, March

What antibiotics are treated for ureaplasma


  • 1 Key aspects of disease management
  • 2 Treatment of ureaplasmosis during pregnancy
  • 3 Contraindications to taking antibacterial medicinal products
  • 4 Basics of antibiotic therapy in women and men

    • 4.1 Doxycycline
    • 4.2 Macropen
    • 4.3 Erythromycin
    • 4.4 Ofloxacin
    • 4.5 Amoxicillin

Ureaplasma is a pathogenic microorganism that lives in the human body, capable of causing ureaplasmosis of varying severity. It is possible to speak about the presence of the pathogen only on the basis of titer indicators.

Key aspects of disease treatment



An antibiotic from ureaplasma is indicated almost always, for any form of pathology. Preparations are selected only by the attending physician, guided by a whole range of requirements. The main circumstances that are taken into account when forming the antibacterial scheme of exposure to the patient:

  1. The sensitivity of the pathogen to an antibiotic;
  2. Study of all possible contraindications;
  3. The correct combination of antibacterial agents and other medicinal products that the patient will take at the same time.

Treatment of ureaplasmosis during pregnancy


Treatment of ureaplasmosis during pregnancy

The question regarding the treatment of ureaplasma with antibiotics during pregnancy is controversial and controversial. In the first trimester, no antibiotic should be taken. In the second and third trimester, some medications are allowed, but only if the infection itself poses a greater threat to the life of the mother or child than the expected harm from active antibiotic therapy.

It is strictly forbidden to select drugs for yourself and take them at your own discretion. In any case, this will cause irreparable damage to the health of the child. Moreover, experimenting with antibacterial agents is unlikely to bring the desired result.

Contraindications for taking antibacterial medicinal products

It is impossible to treat ureaplasmosis with antibiotics of a specific type if patients have an allergic reaction to this type of drugs. Any antibacterial product belongs to the category of highly allergenic substances, which should always be prescribed with extreme caution.

In addition, the following circumstances may be general contraindications to taking this or that drug:

  1. Severe dysbiosis. Antibiotics for the treatment of ureaplasma, like drugs for the treatment of other forms of infection, have a detrimental effect on the intestinal microflora and on the work of this section of the digestive tract in principle. If the patient already has a severe disorder, then antimicrobial agents will further exacerbate the problem. It is possible to prescribe such medications only after the stabilization of the digestive cycle. It is also important to take care of additional protection of the intestinal microflora at the time of taking antibiotics. Probiotics are usually given to the patient.
  2. Pregnancy and active lactation period. Antibiotics against ureaplasma are prescribed only if the patient's condition does not allow to take a waiting position for too long.
  3. Acute or chronic (severe) kidney or liver failure. Damaged or emaciated organs will not be able to cope with such a serious load.

The basics of antibiotic therapy in women and men


The basics of antibiotic therapy in women and men

Antibiotics for the treatment of ureaplasma in women are selected depending on the circumstances in each specific situation. The doctor takes into account the severity of the disease, the form (acute or chronic), the presence of concomitant pathologies, the body's susceptibility to one or another drug. Treatment for men follows a similar principle. In many ways, the success of treatment depends on the sensitivity of the pathogen to a particular type of drug.

The table below shows the indicators of sensitivity and resistance of the causative agent of ureaplasmosis to various types of antibiotics. Based on these indicators, doctors select drugs for treatment.

Group of antibacterial agents Name of specific drugs Sensitivity (%) Stability (%)
Macrolides Macropen 90 ten
Tetracyclines Duxcycline 87 13
Fluoroquinolones Ofloxacin 73 27
Lincosamides Clindamycin 72 28
Aminoglycosides Gentamicin 72 28
Macrolides Erythromycin 56 44
Fluoroquinolones Pefloxacin 50 50
Tetracyclines Tetracycline 46 54

To understand how ureaplasma is treated, which antibiotic is the best for a given disease, a detailed study of the most popular antibiotics will help.



Doxycycline is a broad-spectrum semi-synthetic drug belonging to the tetracycline group. It has a special bacteriostatic effect. The drug is administered orally after a meal. The tablet is taken with plenty of liquid.

The daily dosage is usually calculated per dose. If necessary, a treatment regimen is developed with a double dose of pills (with a break of 12 hours).

If ureaplasma is diagnosed, antibiotics are taken according to the following scheme:

  • First day - 200 mg;
  • Second day - 200 mg;
  • Subsequent days - 100 mg.

If the disease is severe, the patient can take the maximum allowable dosage for longer. The course of treatment is 14 days. In some situations, it is permissible to combine Doxycycline and other antibacterial agents. Popular “partners” are Gentamicin and Clindamycin.

Side effects include the following:

  • Epigastric pain;
  • Swelling;
  • Itching;
  • Diarrhea;
  • Excessive sweating;
  • Dizziness;
  • Candidiasis of various localization.



Macropen is a typical drug in the Macrolide class. The active substance at the heart of the antibiotic is midecamycin. The remedy is taken before the main meal. The maximum daily "adult" dose is 1.6 grams. Children who weigh more than 30 kg are prescribed 1 tablet (400 mg) three times a day. The therapy lasts no more than 10 days.

Adverse reactions:

  • Poor appetite;
  • Nausea;
  • Vomiting urge;
  • An increase in the level of liver enzymes;
  • Allergic reactions.

Pregnant women who have been struck by ureaplasma can use an antibiotic in the second and third trimester. The drug is prescribed only in extreme cases.



Erythromycin is a drug prescribed at the initial stages of the formation of ureaplasmosis. One time an adult is prescribed 500 mg. The maximum daily dose is 2 grams. The duration of treatment is 7 days.

The drug should not be prescribed to pregnant and lactating patients, people who have allergies, hearing problems, as well as severe liver and kidney ailments. It is strictly forbidden to combine Erythromycin with Astemizole and Terfenadine.

The drug can cause quite a few undesirable reactions:

  1. Nausea;
  2. Vomiting;
  3. Complete loss of appetite;
  4. Allergic reactions;
  5. Arrhythmia;
  6. Fungal lesions;
  7. Colitis;
  8. Malfunction of the pancreas.

Given that side reactions occur quite often, this type of antibiotic is prescribed only when urgently needed. In other cases, doctors prefer milder types of antibacterial agents.



Ofloxacin is a popular drug that is valued for its fast absorption and almost complete bioavailability. The active substances are able to penetrate into the organs of the genitourinary system, taking into account both female and male physiology.

When choosing a dosage, the doctor takes into account the fact that the tablets in no case should be crushed or crumbled. They are accepted only whole. It is recommended to take Ofloxacin 400 mg twice a day. The average course of therapy is no more than 10 (not less than 5) days.

The drug should not be combined with anti-inflammatory pharmacological products. Otherwise, additional stimulation of the nervous system may occur, which is highly undesirable. The antibiotic can be replaced with Ciprofloxacin, which also belongs to the category of fluoroquinolones.



Amoxicillin is a drug of the penicillin group. Antibiotics for this type of ureaplasma are often prescribed. However, Amoxicillin cannot always be used. Absolute contraindications - infectious mononucleosis, lymphoproliferative type diseases, severe pathologies of the digestive tract, ARVI, asthma of any type and severity, allergic status.

It is worth noting that Amoxicillin is particularly effective. The main problematic of therapy is the high variability of effects in combination with different medications. Being clearly guided in the questions of which antibiotics can be used to treat ureaplasma, and which drugs cannot be combined with Amoxicillin, the doctor will minimize the risk of side reactions and will also speed up the healing process.

Key aspects of a competent drug combination:

  1. The combination of Amoxicillin and Metronidazole increases the risk of neurological disorders;
  2. Probenecid enhances the antibacterial effect of Amoxicillin;
  3. Aminoglycosides, Cephalosporins, Vancomycin and Macrolides are antagonists of Amoxicillin and almost completely suppress its therapeutic effect;







  4. Indirect coagulants thin the blood much more intensively when taking an antibiotic in parallel;
  5. Ascorbic acid accelerates the absorption of the antibacterial product;
  6. Antacids and laxatives slow down the absorption of Amoxicillin.

Side effects are rare, but they can cause serious discomfort. We are talking about joint pain, ataxia, convulsive conditions, problems with stool. In fact, any antibiotics for ureaplasma are prescribed with extreme caution. An improperly selected drug will only increase resistance and also make further treatment more problematic.

It is also worth recalling once again that antibiotics can only be prescribed by the attending physician, taking into account all aspects of the problem that had to be faced.

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