MEPACRIN - Instructions For Use, Price, Reviews And Analogues

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MEPACRIN - Instructions For Use, Price, Reviews And Analogues
MEPACRIN - Instructions For Use, Price, Reviews And Analogues

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Video: Pharmacology - DRUGS FOR DIABETES (MADE EASY) 2023, February

When and why the drug Mepacrine is used


  • 1 Description of the drug Mepacrine
  • 2 Indications and contraindications
  • 3 Mepacrine: instructions for use

    3.1 Side effects of the drug

  • 4 Analogues of Mepacrine
  • 5 Reviews of the drug Mepacrine

The problem of the appearance of worms in the human body remains relevant for many years. Helminths can appear due to insufficient hygiene, eating contaminated foods, and many other reasons. To remove parasites from the body, there are a large number of drugs, each of which has either a complex effect, or is actively fighting a separate category of worms. One of the most popular anthelmintics is Mepacrine.

Description of the drug Mepacrine


Description of the drug Mepacrine

Mepacrine is a broad-spectrum anthelmintic agent designed to combat malaria, lamblia and intestinal worms. This drug is notable for its low cost, as well as high efficiency, since it affects not only adults, but also the larvae of parasites.

The drug is highly toxic, so it is dispensed in pharmacies as prescribed by a doctor. After entering the human body, the constituents of Mepacrine begin to destructively affect the outer membranes of the parasites - damaging them and disrupting the respiratory function. This product is intended solely to remove parasites from the body. Experts do not recommend taking the drug as a therapeutic or prophylactic, since its components are synthesized in the liver and excreted through bile and urine.

Mepacrine is marketed in the form of tablets or a special solution for injection. Use without medical advice is strictly prohibited.

Indications and contraindications

The broad-spectrum antiparasitic agent Mepacrine is prescribed when the following diseases are detected:

  • Diphyllobothriasis - a lesion caused by a wide lancet;
  • Teniarinhoz (bovine tapeworm);
  • Hymenolepiasis;
  • Malaria;
  • Leishmaniasis;
  • Lupus erythematosus.

The remedy is also prescribed for the treatment of psoriasis, giardiasis and some other types of diseases, for the treatment of which complex methods are used.

Mepacrine is categorically contraindicated in manifestations of mental instability (psychosis and schizophrenia), renal failure, jaundice, as well as in case of an allergic reaction to a separate component of the drug. It is also worth refusing to take the drug while breastfeeding and during pregnancy, since its components can negatively affect the development of the fetus or newborn.

Mepacrine has an immunosuppressive effect and is prohibited in the presence of other diseases. Before use, a mandatory consultation with your doctor is required.

The drug is used to treat parasitic infestations in different age groups. Also, the tool is used during the prevention of malaria in infants, and the maximum positive effect is observed not only with the correct dosage, but also with high hygiene and diet.

Mepacrine: instructions for use

The dosage of the drug during anthelmintic therapy depends on the age of the patient. Experts distinguish two age groups:

  • Adults;
  • Children (from birth to 16 years old);
  • Aged people.

The dosage of the drug is calculated based on the type of parasitic lesion:

  • Malaria - the duration of the course of treatment is 4 days, during which the patient needs to drink 1.5 g of the drug, dividing the dose into several parts (300 mg in the morning and evening on day 1, on day 2 300 mg once, on days 3 and 4 - 300 mg of the product 1 time);
  • Giardiasis - you need to consume 300 mg of the drug daily for 7 days;
  • Helminthiasis - drink 1-2 tablets once with a pause of up to 10 minutes;
  • Leishmaniasis - for the treatment of this type of parasitic lesion, injections are most often used, and the amount of the drug is calculated individually, based on the patient's indicators.

When treating parasitic lesions in children, the course is calculated based on age indicators:

  • In case of malaria in infants (up to 1 year old), it is necessary to take 100 mg of the drug for 3 days (2 times 0.025 g for 1 day, and the same amount for 2 and 3 days once);
  • 1-2 years - from this period, the duration of the course is 4 days, and the dosage is 200 mg;
  • At the age of 2-4 years, the dosage rises to 400 mg;
  • At 6-12 years old - 600-800 mg;
  • From 12 to 16 years old - 1000 mg;
  • You can also use the drug for helminthic invasions under the age of 2 years, but the daily dose of the drug should not exceed 15 mg;
  • For the treatment of giardiasis, the dosage is calculated based on the weight of the child - no more than 300 mg per day, 2 mg per kilogram.

Although the drug can be prescribed for the treatment of various parasitic lesions in children, before taking it, it is necessary to consult with a doctor regarding more careful means intended for certain age categories, since with an incorrectly calculated dose, the child's body may not cope with the increased load and side symptoms will appear.

Side effects of the drug

With the wrong dosage or individual intolerance to the drug, as well as its individual components, the following side symptoms may occur:

  • Local or general allergic reaction;
  • The urine becomes dark yellow;
  • Mental disorders accompanied by depression and hallucinations;
  • Difficulties in orientation in space.

In the case of prolonged use of Mepacrine, yellowish skin staining may also occur. Such a reaction is observed in cases where the liver cannot cope with the increased load and the components, instead of being excreted from the body, are deposited in various tissues.

In order to avoid the manifestation of side effects, it is necessary to conduct a thorough examination of the patient for violations in the working capacity of the liver and kidneys, as well as to check the mental state.

If side symptoms appear, you should immediately stop taking the drug and visit your doctor as soon as possible. If the drug has shown a negative effect after the first dose, it is necessary to pause for 7-10 days, then replace the drug with a more suitable one, based on the individual characteristics of the patient's body.

Analogs of Mepacrine

Mepacrine can be found in pharmacies under the following names:

  • Akrikhin;
  • Atabrin;
  • Mepacrine Hydrochloride;
  • Tenicridine and others.





If we talk about structural analogs, then it is almost impossible to find those on sale. The most similar in terms of their effect are drugs:

  • Fenasal - the main active ingredient is niklomazid, which affects a wider range of parasites;
  • Nemozol is used to treat giardiasis in children over 1 year old and is distributed both in the form of tablets and in the form of suspensions.





Mepacrine is a fairly strong antiparasitic agent designed to treat malaria, giardiasis, and some types of helminthiasis. The drug has high toxicity rates, as a result of which there is a high likelihood of side effects, especially in case of disorders in the liver and kidneys.

The tool can be used to treat parasitic infestations in children, but only under strict medical supervision. To eliminate worms during breastfeeding, it is recommended to replace the drug with a more gentle one, for example, Nemozol. There is no need to try to get rid of parasites on your own - be sure to consult a specialist before taking it.

Reviews about the drug Mepacrine

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