Table of contents:
- 1 Composition and description
- 2 Instructions for use of the drug
- 3 Contraindications
- 4 Side effects
- 5 Analogs
Many negative factors reduce the immune status of a person, which leads to the emergence of infectious diseases and the penetration of pathogens. During this period, it is extremely important to stop pathological processes, to prevent damage to vital organs and internal systems. Augmentin 500 mg (amoxicillin trihydrate) + 125 milligrams of clavulanic acid are prescribed as antibacterial and bactericidal properties. So, let's figure out what a drug is, what forms of release it has, and how to take the medication correctly.
Composition and description
Augmentin is a combined drug that includes amoxicillin trihydrate and clavulanic acid. Additionally, there are excipients that do not have antibacterial activity.
You can purchase the medicine in the following dosage forms:
- Tablets 500 mg plus 125 mg, 250 mg plus 125 mg (Augmentin 400 mg) and 875 mg plus 125 mg. The first dosage is amoxicillin trihydrate, the second is clavulanic acid;
- The powder used to dilute the solution. It comes in a dose of 200 mg; 400 mg and 125 mg;
- Powder for preparation of liquid for injection in dosages of 500 and 1000 mg;
- Augmentin 5 ml, intended for the preparation of suspensions;
- Sustained-release tablet form. The dosage is 1000 mg by 62.5 mg.
Augmentin 200 mg and other dosages belong to the pharmaceutical group of antibacterial drugs that are recommended for systemic use. The main action is antibacterial, the auxiliary effect is bactericidal.
Two active components after oral administration are rapidly absorbed in the gastrointestinal tract. Maximum absorption is observed if tablets or Augmentin in the form of a suspension for children are taken before meals.
Instructions for using the drug
The main indication for use is the presence of pathogenic or opportunistic bacteria, which are hypersensitive to the active ingredients of the drug.
It is advisable to use Augmentin for the treatment of infectious pathologies that have developed as a result of the activity of bacteria sensitive to the substance amoxicillin, as well as mixed infections.
The antibiotic Augmentin for children has a fairly wide range of indications for use for the treatment of infectious and inflammatory pathologies:
- Infectious processes in the body that occur in the upper and lower respiratory tract;
- Infectious diseases affecting the genitourinary system;
- Gynecological and odontogenic infections;
- Inflammatory processes manifested in soft tissues and on the skin;
- Bone infections, etc.
The instructions for use state that tablets / syrup and other forms of the drug are often prescribed before extensive surgery on the head, neck, in the gastrointestinal tract in order to prevent inflammation and infection.
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Doses of the drug for babies and adults depend on the age group of the patient, the specific type of pathogen that provoked the pathological process, body weight and the condition of the patient's kidneys. The duration of the treatment course is due to the body's response to therapy.
Features of the use of tablets:
- The tablet form is more often recommended for patients over 18 years of age;
- The product at a dosage of 375 mg must be used 3 times a day. In other words, take one capsule at a time;
- If a severe infectious process is diagnosed, the dosage may increase at the discretion of the attending physician and the tolerability of treatment;
- Tablets in a dose of 1000 mg are taken 2 times in 24 hours (one at a time).
Augmentin of prolonged effect may be prescribed to patients who are over 16 years of age. The dosage is two tablets in 24 hours, the frequency of use is no more than twice a day.
Instructions for using the suspension for a child:
- Suspension in a dose of 125 mg, equal to a dose of 2.5 to 20 ml. It is used 3 times a day, a single dosage is due to the patient's age, specific pathogenic microorganism, and body weight.
- If the baby is older than two years, then the dose varies from 25 to 45 mg per kilogram of weight; is divided into two uses.
- A suspension with a dosage of active ingredients of 400 mg per 57 mg is prescribed for only one year. One-time ranges from 5 to 10 ml. It can be used no more than two times per day.
In childhood, Augmentin for angina is recommended depending on the weight and age group of the baby. For the treatment of angina in an adult, the dose is 875 plus 125 mg up to three times a day.
Augmentin appears as a drug with antibacterial properties that helps to destroy pathogenic microorganisms. The remedy is quite strong and powerful, has a pronounced therapeutic effect, and has relatively many contraindications.
Regardless of the dosage form, Augmentin is not prescribed in the following situations:
- Organic intolerance to one or two active components of the drug, or auxiliary components;
- Patients in whom treatment with Augmentin preceded episodes of jaundice or organic liver disorders are present in the medical history due to the use of amoxicillin trihydrate and clavulanic acid.
It is not recommended to use powders for preparing a suspension inside with dosages of 200 and 400 mg if the patient has phenylketonuria, impaired renal function (provided that the Reberg test shows a result of less than 30 ml in 60 seconds). Also, do not appoint young children who are not three months old.
Tablets in a dosage of 1000 mg are not recommended for use:
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- Some kidney pathologies;
- Children under 12;
- Body weight up to 40 kilograms.
The attending doctor decides on the appropriateness of using the drug in a given situation. The remedy gives a quick healing effect, but has relatively many side effects. Requires medical supervision during treatment.
In accordance with the instructions for use, adverse events are subdivided into those that develop often, relatively rarely and rarely, and can also occur when certain negative factors are involved.
In most clinical pictures, an antibiotic leads to the development of the following adverse reactions:
- Thrush that affects the skin and mucous membranes;
- Disruption of the digestive tract, manifested by prolonged diarrhea;
- Nausea, up to vomiting (this reaction is most often the result of an overdose of the drug).
Relatively rare side effects include migraine, dizziness, impaired digestion, increased activity of liver enzymes, allergic manifestations in the form of itching, burning, and skin rashes.
Possible negative phenomena include the following reactions from the human body:
- Hemolytic form of anemia.
- A pathological condition, which is accompanied by an increase in the duration of bleeding.
- Reactions from the immune status, which are expressed by Quincke's edema, a syndrome of the type of serum sickness.
- Reversible hyperactivity.
- Convulsive state.
- Colitis due to the use of antibacterial drugs.
- Salt crystals are observed in urine.
If, as a result of taking the drug, an allergic form of dermatitis has developed, then the use of Augmentin is stopped immediately. In this case, it is required to select an analogue of a medication that has a similar therapeutic effect.
The analogs of the drug include A-Clav-Pharmex, Amoxil-K, Amoxiclav, Medoklav and other drugs. Replacement is carried out only by a medical specialist if there are indications, for example, the development of pronounced adverse reactions due to taking Augmentin.
- A-Clav-Pharmex is a product that contains the same active ingredients as Augmentin. It is not recommended to use during pregnancy, breastfeeding, with a history of jaundice. Side effects include prolonged diarrhea, abdominal pain, headaches, dizziness, and skin reactions. The dosage depends on the body weight and age group of the patient. There are several dosage forms of the drug;
- Amoxil-K. Sold only in tablet form. Unlike the drug Augmentin, it has a smaller list of contraindications for use. These include dysfunction of the liver, jaundice associated with the use of a medication. The dose is assigned individually. The remedy is well tolerated; negative reactions from organs and systems very rarely develop.
Antibacterial drugs are sold only with a doctor's prescription. To achieve the desired result, it is recommended to strictly adhere to the dosage and frequency of use, which also reduces the risk of side effects.