Pirantel: Suspension For Children From Worms - Application

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Pirantel: Suspension For Children From Worms - Application
Pirantel: Suspension For Children From Worms - Application

Video: Pirantel: Suspension For Children From Worms - Application

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Video: Pyrantel Pamoate Overview 2023, February
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Pirantel for children from worms is an effective drug, about which there are many positive reviews. The suspension has a wide spectrum of action; it fights several types of helminths at once.

The content of the article:

  • 1 Medicinal product Pirantel
  • 2 Composition and release form of the drug Pirantel
  • 3 Pharmacological properties of the drug
  • 4 Indications for use of the drug
  • 5 Syrup for children
  • 6 Form of issue, composition and packaging
  • 7 What substance is included in the suspension and how does it work
  • 8 When using the drug Pirantel suspension for children
  • 9 Benefits of Pirantel suspension for children
  • 10 Action of the suspension for children
  • 11 Contraindications and side effects of the suspension
  • 12 Features of taking Pirantel suspension by children
  • 13 Methods of administration and dosage of the suspension for children
  • 14 Drug analogs

Pirantel drug

Pirantel (possible trade names: Pirantel pamoat, Helmintox, Nemocid, etc.) is a well-known and effective antihelminthic agent. After oral administration, Pirantel kills various types of worms (including roundworms and pinworms). Pirantel has a detrimental effect on adult worms.

Pirantel suspension for children
Pirantel suspension for children

Pirantel is an anthelmintic drug. Acts on worms, disrupting the transmission of nerve impulses in the muscles. Pirantel: instructions for use indicate that the active substance in its composition is pyrantel pamoate. In addition, it contains the following auxiliary components: potato starch; microcrystalline cellulose; magnesium stearate; sodium carboxymethyl starch.

Do not take Pirantel if you have ever been allergic to this medicine.

Before you start taking Pirantel, be sure to tell your doctor if you suffer from chronic liver disease or if your last blood tests showed signs of liver dysfunction (increased levels of ALT, AST, bilirubin).

Taking Pirantel can cause dizziness, therefore, during treatment, you should drive a car with caution, or refuse to perform other tasks that require increased concentration.

Pirantel suspension for children
Pirantel suspension for children

The safety of Pirantel in the treatment of children has not been studied. In this regard, Pirantel pamoat is not recommended for children under 2 years of age, unless it is recommended by the attending physician.

Pyrantel chewable tablets contain phenylalanine, therefore it may be contraindicated in phenylketonuria.

When taken with Pirantel, medicines containing Theophylline (for example, Ventax, Theotard, Theostat, Teopek, etc.) can cause dangerous side effects, so be sure to tell your doctor if you are taking any other medicines before taking Pirantel.

Composition and release form of the drug Pirantel

The medicine comes in two forms: tablets and suspensions.

250 mg tablets are cylindrical in shape, on the one hand there is a risk. They are yellow in color, available in cans of 3 or 6 pieces. The active ingredient is pyrantel pamoate.

Excipients: gelatin; starch; magnesium stearate; propyl parahydroxybenzoate; methyl parahydroxybenzoate; sodium carboxymethyl starch; acacia gum; colloidal silicon dioxide; talc.

Under the influence of light, the tablets darken and acquire a brownish tint. Available in blisters of 3 or aluminum strips.

Pirantel suspension is a homogeneous liquid with a pleasant taste, yellow in color. Available in 15 ml glass bottles. Excipients: sucrose; sorbitol 70%; flavors; purified water; sorbic acid; xanthan gum; polysorbate 80; methyl parahydroxybenzoa; propyl parahydroxybenzoate.

Pirantel suspension for children
Pirantel suspension for children

Suspension for oral administration is a yellowish viscous liquid with a characteristic odor and caramel taste. Packaged in 15 ml dark glass bottles. The lid can be used as a dispenser.

The suspension and tablets contain the same amount of active ingredient, and the patient can choose a convenient form of administration.

The tablets are designed for a single use of the drug in a larger dose. They are suitable for adults and children over 3-5 years old. For the smallest patients, it will be convenient to take the drug in the form of a suspension.

Pharmacological properties of the drug

Pirantel causes neuromuscular blockade in sensitive helminths. Thanks to the competently combined composition, the drug is effective against Enterobius vermicularis, Ancylostoma duodenale, Necator americanus, Trichocephalus trichiurus.

The active substance affects only sexually mature individuals and does not affect the eggs of worms or larvae of helminths that are in the migration stage. The components of the composition are practically not absorbed from the gastrointestinal tract (gastrointestinal tract).

After taking a single dose, the maximum concentration of the active substance in the plasma is reached within 1-3 hours.

Pyrantel is partially decomposed into components under the influence of liver enzymes. 93% is excreted unchanged through the intestines along with feces, the remaining 7% are excreted in the form of metabolites in the urine.

Indications for the use of the drug

Pirantel is used for enterobiasis, ankylostomiasis, ascariasis, and noncatorosis. Pirantel tablets should be taken orally 1 time / day. The drug is taken at any time, regardless of food.

Pirantel suspension for children
Pirantel suspension for children

The drug is taken at any time, regardless of food.

Indications for use:

  • for enterobiasis, as well as for ascariasis and enterobiasis for children and adults, the drug Pirantel is used once at a dose of 10 mg / kg of body weight. In severe forms, a double dose of the drug is used for 2-3 days - 20 mg / kg / day (used once or divided into 2 doses). In order to prevent self-infection, it is recommended to take Pirantel again after 3 weeks at a dose of 10 mg / kg;
  • in the treatment of isolated ascariasis, Pirantel should be taken once at a dose of 5 mg / kg;
  • in case of hookworm infection, noncatorosis, simultaneous invasion by nekator and ascaris, or with other mixed invasions, the drug Pirantel is used at 10 mg / kg / day for 3 days or at 20 mg / kg / day for 2 days.

For children under 3 years of age, Pirantel is used in the form of an oral suspension. Shake the bottle before using the suspension.

The suspension is taken orally (inside). With enterobiasis and ascariasis, the dose is usually 10-12 mg / kg of body weight per dose.

Suspension for children over 6 months old is used at 2.5 ml per 10 kg of body weight at a time. Adults weighing less than 75 kg use 15 ml of suspension for 1 dose, and those weighing more than 75 kg - 20 ml of suspension for 1 dose.

When treating enterobiasis, in order to consolidate the therapeutic effect, it is recommended to follow the rules of personal hygiene (in particular, for children), as well as repeat the course of treatment after 3 weeks.

Pirantel suspension for children
Pirantel suspension for children

In case of an overdose of Pirantel, the following symptoms develop: diarrhea, nausea, anorexia, vomiting, ataxia.

In case of hookworm infection in case of severe invasion or in case of a disease in an endemic zone, the drug should be used at 20 mg / kg / day in 1-2 doses for 2-3 days.

In the event of an invasion in a non-endemic zone, a single use of Pirantel at a dose of 10 mg / kg of body weight is usually sufficient. In case of an overdose with Pirantel, gastric lavage is necessary. It is also required to monitor the work of the respiratory system and the cardiovascular system. There is no specific antidote.

Syrup for children

Pirantel suspension for children
Pirantel suspension for children

Its uniqueness lies in the least degree of toxic effects on the body. Children's age is considered the most vulnerable, it is children who most often become infected with infectious diseases, they often have cases of colonization of parasites.

A large children's team in the kindergarten, the inability to always control the cleanliness of the hands leads to the fact that helminth eggs enter the child's body and turn into large individuals.

An important task for parents is to choose the safest and most effective medicine to eliminate the problem. Pirantel suspension is one of the most popular drugs for getting rid of worms.

Release form, composition and packaging

Pirantel suspension for children
Pirantel suspension for children

Suspension for oral administration is light yellow in color, with a characteristic odor; separation into a liquid layer and sediment is allowed, after shaking a homogeneous suspension is formed.

Excipients: sodium benzoate - 15 mg, sodium carmellose - 15 mg, sorbitol 70% (non-crystallizing) - 3605 mg, glycerol - 303.5 mg, magnesium aluminosilicate - 16.5 mg, polysorbate 80 - 10 mg, povidone K25 - 100 mg, citric acid monohydrate - 1.5 mg, simethicone emulsion - 2.5 mg, fruit flavor - 2.5 mg, water - up to 5 ml.

  • 5 ml - bottles (1) complete with a measuring cup or measuring spoon - cardboard packs.
  • 10 ml - bottles (1) complete with a measuring cup or measuring spoon - cardboard packs.
  • 15 ml - bottles (1) complete with a measuring cup or measuring spoon - cardboard packs.
  • 25 ml - bottles (1) complete with a measuring cup or measuring spoon - cardboard packs.

What substance is included in the suspension and how does it work

The "Pirantel" suspension contains an active ingredient - pyrantel pamoate, which is a broad-spectrum antihelminthic agent.

To stay in the intestines, many worms must constantly move, otherwise the contractions in the intestines will push them out.

"Pirantel" is almost not absorbed in the intestines, therefore it does not have a strong effect on the child's body.

Pirantela pamoat suppresses neuromuscular conduction in parasites, as a result of which immobilized individuals are freely excreted from the body. "Pirantel" expels sexually mature and immature worms of both sexes, and is ineffective only against migrating roundworm larvae.

When to use the drug Pirantel suspension for children

Pirantel suspension for children
Pirantel suspension for children

The drug for children is prescribed for infection with worms. Most often in our strip there are roundworms (the disease will be called ascariasis) and pinworms (enterobiasis).

Many children are carriers of intestinal helminths (worms), but helminthiasis is difficult to diagnose, because similar symptoms can occur in other diseases, and in the analysis of feces, helminth eggs cannot always be detected. However, if a doctor has diagnosed an infection with worms, Pirantel is a safe means of dealing with them.

Benefits of Pirantel suspension for children

Parents often opt for suspensions for children. The advantage of the drug in comparison with syrups of a similar action lies in two factors:

  • Pirantel can be given to children if several types of roundworms are found. It helps to effectively get rid of the most common worms: ascoris and pinworms;
  • syrup contains a substance that paralyzes worms. After taking it, there is no need to give laxatives to children so that the residues come out.

The uncontrolled prescription of the drug is strictly prohibited. Only a specialist can prescribe a syrup intake.

Suspension action for children

The Pirantel suspension from worms for children is well tolerated by children, as it has a pleasant taste, in contrast to tablets of a similar action.

Pirantel suspension for children
Pirantel suspension for children

How does the suspension work? The active substance that is part of the drug paralyzes roundworms. Paralyzed helminths do not die, but their development slows down. They begin to move very slowly in the intestines.

This promotes the elimination of worms from the body naturally. The child does not need to use additional laxatives. Instructions for the use of Pirantel syrup says that the worms go out with the child's feces.

The effect of the drug lasts no more than 24 hours, then it is excreted from the body. It reaches the highest concentration in the body an hour after ingestion.

Precisely because the remedy does not kill parasites, but paralyzes them, the body does not poison. This is very important when it comes to treating young children. Thanks to this, the suspension does not have a negative effect on the body. Already on day 1, the worms are removed from the intestines.

Contraindications and side effects of the suspension

Pirantel syrup, like any other drugs, have contraindications. The tool should not be taken if there is an individual intolerance to the components.

Reception is contraindicated in adults and children who have been diagnosed with myasthenia gravis, and they are being treated. It is an autoimmune disease in which muscles fatigue constantly.

Pirantel suspension for children
Pirantel suspension for children

It is not recommended to give the remedy to children under six months of age, despite the fact that it is considered safe.

With caution and only under the supervision of a doctor, you can drink Pirantel for those who have liver failure. This is due to the fact that the active components of the drug are absorbed by the liver.

Side effects when taking the drug can occur only in case of an overdose.

Side effects include:

  • from the gastrointestinal tract - vomiting, nausea, diarrhea, abdominal pain;
  • the patient may have disturbed sleep, nervousness, dizziness, headaches may appear. There have been cases of hallucinations;
  • children may experience allergic reactions in the form of itching, rash, fever.

If such symptoms appear, the drug should be stopped and a doctor should be consulted.

Features of taking Pirantel suspension by children

Before you start giving the suspension to the child, you must carefully study the instructions for use. To prevent uncontrolled intake of the drug, in the pharmacy chain it is sold only with a prescription.

There are several rules for taking the drug:

  • if syrup and tablets are used to treat enterobiasis, all family members should take the drugs;
  • control over the effectiveness of the agent should be carried out through the delivery of clinical analyzes of feces for ovarian tissue;
  • the drug can be taken by pregnant and lactating women only as directed by a doctor. This takes into account what is greater: the risk of harm caused by parasites or drugs;
  • it is not recommended to combine taking Pirantel with other antihelminthic drugs. This can reduce the activity of the active substance;
  • the components of the drug can increase the concentration of theophylline in the blood;
  • there is evidence that taking the drug affects the speed of psychomotor reactions. In this regard, adults who drink this drug need to be careful while driving.

Methods of administration and dosage of the suspension for children

How to take Pirantel for children? The dosage should be prescribed by a specialist.

Pirantel suspension for children
Pirantel suspension for children

It is calculated taking into account the age and weight of the patient. 10 mg of the drug goes to one kilogram of weight.

  • when setting the dose, not only age and weight are taken into account, but also the degree of damage to the body by worms. Such information becomes clear when collecting analyzes;
  • children under 2 years old are prescribed 2.5 ml of suspension;
  • by the age of 6 years, the dosage is doubled.

You can take Pirantel Pharma only with food or immediately after it. How many days should the course of treatment last? The duration of treatment directly depends on the causative agent of the disease. When infected with pinworms or roundworms, a single use of the drug is needed.

The course of treatment will last three days if hookworms are found in the body. Within three days, you must take one dose once a day.

Most often, the disease completely disappears after one course of admission. But experts recommend repeating the course in 15-20 days. This is due to the fact that repeated cases of infection are often observed.

Drug analogues

If Pirantel Pharma is contraindicated for use, doctors may prescribe drug analogues. Medamin is considered the best alternative. It is considered to be just as effective and safe. The action of the drug is aimed at disrupting the metabolism of worms.

Pirantel suspension for children
Pirantel suspension for children

The parasite disrupts the work of the nervous system, and subsequently dies. The active components of the tablets stop the migration of larvae.

Tablets are taken in crushed form with warm water. Unlike Pirantela Pharma, Medamin is contraindicated in children under three years of age.

Another analogue of Parantel is Mintezol tablets. The drug fights well with both adults and migratory larvae. The drug is contraindicated in children under 15 kg. and pregnant women.

Find out more:

  • Symptoms of worms in a child. Signs of worms in children
  • Worms in children: folk remedies and treatment methods
  • Pinworms in children - symptoms, treatment, alternative methods

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